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Università della Svizzera italiana

Loss and revival of androgen receptor signaling in advanced prostate cancer

Formaggio, Nicolò ; Rubin, Mark A. ; Theurillat, Jean-Philippe

In: Oncogene, 2021, vol. 40, no. 7, p. 1205–1216

Targeting the androgen receptor (AR) signaling axis has been, over decades, the mainstay of prostate cancer therapy. More potent inhibitors of androgen synthesis and antiandrogens have emerged and have been successfully i mplemented in clinical practice. That said, the stronger inhibition of the AR signaling axis has led in recent years to an increase of prostate cancers that de-differentiate...

  • Chandrasekar T, Yang JC, Gao AC, Evans CP....
  • Gao S, Gao Y, He HH, Han D, Han W, Avery A, et al....
  • Berman-Booty LD, Knudsen KE....
Consortium of Swiss Academic Libraries

Variations on gui and the Trouble with Ghosts in Modern Chinese Fiction

Imbach, Jessica

In: Asiatische Studien - Études Asiatiques, 2016, vol. 70, no. 3, p. 865-880

  • Parallel to this line of mostly satirical gui allegories developed a strand of leftist ghost literature that targeted specific political enemies....
  • Ouyang Shan 欧阳山 (1988a): “Gao Ganda 高干大 (Uncle Gao)”....
  • Edited by Ke Ling 柯灵....
  • Dashed line outlines compositional range of clinopyroxene from Group I porphyroclastic (grt)-spl lherzolites (Kaeser et al. 2006)....
  • Also indicated for comparison are P–T evolution paths for three mantle rock massifs which have been ¨ exhumed during continental rifting: Malenco [red; Muntener (1997); dashed line peridotite; continuous line grt clinopyroxenite intrusion]; Ligurian grt clinopyroxenites and peridotites [green Montanini et al. (2006)]; Zabargad, former garnet-bearing websterites and spl peridotites [hachured field; Piccardo et al. (1988)]....
  • Lithos 54:83–114 Liu YS, Gao S, Lee CTA, Hu SH, Liu XM, Yuan HL (2005) Meltperidotite interactions: links between garnet pyroxenite and high-Mg# signature of continental crust....
  • Gao-PTXi M17526: (pcDNA3) contains C351G, and Gao-PTXi/RGSi (pcDNA3) contains G184S/C351G (see [42])....
  • This difference might be due to differences among cell lines or perhaps the placement of the epitope tag....
  • Tinker for Gao-PTXi and Gao-PTXiRGSi cDNA....
  • Pedersen-Bjergaard S, Rasmussen KE (1999) Anal Chem 71 (14):2650–2656 50....
  • Ho TS, Pedersen-Bjergaard S, Rasmussen KE (2002) Analyst 127(5):608–613 56....
  • Gao W, Chen G, Chen Y, Li N, Chen T, Hu Z (2011) J Chromatogr A 1218(33):5712–5717 129....
Université de Fribourg

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica

Pu, Wei-ling ; Sun, Li-kang ; Gao, Xiu-mei ; Rüegg, Curzio ; Cuendet, Muriel ; Hottiger, Micheal O. ; Zhou, Kun ; Miao, Lin ; Zhang, Yun-sha ; Gebauer, Margaret

In: Chinese Journal of Integrative Medicine, 2017, vol. 23, no. 10, p. 723–732

Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment....

  • Effect of berberine on mice Gao S, Zhou J, Liu N, Wang LJ, Gao QY, Wu Y, et al....
  • Lin Q....
  • Lin Z....
  • Lin....
  • Gao, T....
  • Ke, W....
Université de Fribourg

Luminescent acetylthiol derivative tripodal osmium(II) and iridium(III) complexes: Spectroscopy in solution and on surfaces

Ramachandra, Srinidhi ; Polo, Federico ; Edafe, Fabio ; Schuermann, Klaus C. ; Nijhuis, Christian A. ; Belser, Peter ; Reus, William F. ; Whitesides, George M. ; Cola, Luisa De

In: Pure and Applied Chemistry, 2011, vol. 4, no. 83, p. 779-799

Luminescent Os(II) and Ir(III) complexes containing a tripodal-type structure terminalized with three thiol derivatives are described. The tripod is introduced through derivatization, with a rigid spacer, of a phenanthroline ligand coordinated to the metal ion, and the entire structure possesses axial geometry. The geometry of the complexes combined with the three anchoring sites, the thiol...

  • Lin....
  • Gao, T....
  • Ke, W....
  • Gao, S....
  • Gao, S....
  • The posterior five vertebrae are, however, in straight-line articulation with each other....
Bibliothèque cantonale jurassienne

Earliest known crown-group salamanders

Gao, Ke-Qin ; Shubin, Neil

In: Nature : a weekly illustrated journal of science, 2003, vol. 422, p. 424

  • Earliest known crown-group salamanders Ke-Qin Gao*† & Neil H....
  • Gao, K....
  • Gao, K., Cheng, Z. & Xu, X....