In: RSC Advances, 2018, vol. 8, no. 42, p. 23881–23890
Sulfur Mustard (SM) is a blistering agent used as a chemical weapon. Glutathione (GSH) is involved in the β-lyase degradation pathway of SM and recently, bioadducts between SM and GSH were observed in vitro. While these bioadducts have never been isolated from in vivo tests or real poisoning with SM, they could be of interest as potential future biomarkers for the retrospective validation of...
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In: Helvetica Chimica Acta, 2017, vol. 100, no. 11, p. -
Two pathways were developed and investigated for the synthesis of the ‘aged’- nonapeptide nerve-agent bioadduct of human butyrylcholinesterase (BuChE). Considering the fast ageing of nerve-agent adducts of BuChE in patients and biomedical samples this target molecule is of paramount relevance for quantitative analysis with respect to the Chemical Weapons Convention. Two approaches using a ...
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Mémoire de bachelor : Haute Ecole de Santé de Fribourg, 2012.
La communication chez la personne déficiente mentale sévère à profonde est limitée. Ce déficit engendre souvent une sous-évaluation de la douleur. La gestion de cette douleur est primordiale, car une souffrance peut limiter le processus relationnel, déjà difficile chez ces personnes. De plus, elle comporte un aspect éthique car reconnaître la douleur de l’autre c’est le considérer...
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