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Cellular uptake and toxic effects of fine and ultrafine metal-sulfate particles in human A549 lung epithelial cells

Könczöl, Mathias ; Goldenberg, Ella ; Ebeling, Sandra ; Schäfer, Bianca ; Garcia-Käufer, Manuel ; Gminski, Richard ; Grobéty, Bernard ; Rothen-Rutishauser, Barbara ; Merfort, Irmgard ; Giere, Reto ; Mersch-Sundermann, Volker

In: Chemical Research in Toxicology, 2012, p. -

Ambient airborne particulate matter is known to cause various adverse health effects in humans. In a recent study on the environmental impacts of coal and tire combustion in a thermal power station fine crystals of PbSO4 (anglesite), ZnSO4•H2O (gunningite), and CaSO4 (anhydrite) were identified in the stack emissions. Here, we have studied the toxic potential of these sulfate phases as...