Université de Fribourg

The serotonergic central nervous system of the drosophila larva: anatomy and behavioral function

Huser, Annina ; Rohwedder, Astrid ; Apostolopoulou, Anthi A. ; Widmann, Annekathrin ; Pfitzenmaier, Johanna E. R. ; Maiolo, Elena M. ; Selcho, Mareike ; Pauls, Dennis ; Essen, Alina von ; Gupta, Tripti ; Sprecher, Simon G. ; Birman, Serge ; Riemensperger, Thomas ; Stocker, Reinhard F. ; Thum, Andreas S.

In: PLoS ONE, 2012, vol. 7, no. 10, p. e47518

The Drosophila larva has turned into a particularly simple model system for studying the neuronal basis of innate behaviors and higher brain functions. Neuronal networks involved in olfaction, gustation, vision and learning and memory have been described during the last decade, often up to the single-cell level. Thus, most of these sensory networks are substantially defined, from the sensory...

Université de Fribourg

Nutritional value–Dependent and nutritional value–Independent effects on Drosophila melanogaster larval behavior

Rohwedder, Astrid ; Pfitzenmaier, Johanna E. ; Ramsperger, Noel ; Apostolopoulou, Anthi A. ; Widmann, Annekathrin ; Thum, Andreas S.

In: Chemical Senses, 2012, vol. 37, no. 8, p. 711-721

Gustatory stimuli allow an organism not only to orient in its environment toward energy-rich food sources to maintain nutrition but also to avoid unpleasant or even poisonous substrates. For both mammals and insects, sugars—perceived as “sweet”—potentially predict nutritional benefit. Interestingly, even Drosophila adult flies are attracted to most high-potency sweeteners preferred by...

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3 Apostolopoulou, Anthi A.