In: Current Opinion in Immunology, 2004, vol. 16(4), p. 524-530
Theileria parasites infect and transform cells of the ruminant immune system. Continuous proliferation and survival of Theileria-transformed cells involves the well-orchestrated activation of several host-cell signalling pathways. Constitutive NF-κB (nuclear factor kappaB) activation is accomplished by recruiting the IKK (IκB kinase) complex, a central regulator of NF-κB pathways, to the...
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