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Université de Fribourg

Matching–centrality decomposition and the forecasting of new links in networks

Rohr, Rudolf P. ; Naisbit, Russell E. ; Mazza, Christian ; Bersier, Louis-Félix

In: Proc. R. Soc. B, 2016, vol. 283, no. 1824, p. 20152702

Networks play a prominent role in the study of complex systems of interacting entities in biology, sociology, and economics. Despite this diversity, we demonstrate here that a statistical model decomposing networks into matching and centrality components provides a comprehensive and unifying quantification of their architecture. The matching term quantifies the assortative structure in which node...

Université de Fribourg

Self-Organization of plant vascular systems: claims and counter-claims about the flux-based auxin transport model

Feller, Chrystel ; Farcot, Etienne ; Mazza, Christian

In: PLoS ONE, 2015, vol. 10, no. 3, p. e0118238

The plant hormone auxin plays a central role in growth and morphogenesis. In shoot apical meristems, auxin flux is polarized through its interplay with PIN proteins. Concentration-based mathematical models of the flux can explain some aspects of phyllotaxis for the L1 surface layer, where auxin accumulation points act as sinks and develop into primordia. The picture differs in the interior of the...

Université de Fribourg

As the world turns: short-term human spatial memory in egocentric and allocentric coordinates

Banta Lavenex, Pamela A. ; Lecci, , Sandro ; Prêtre, Vincent ; Brandner, Catherine ; Mazza, Christian ; Pasquier, Jérôme ; Lavenex, Pierre

In: Behavioural Brain Research, 2011, vol. 219, no. 1, p. 132-141

We aimed to determine whether human subjects’ reliance on different sources of spatial information encoded in different frames of reference (i.e., egocentric versus allocentric) affects their performance, decision time and memory capacity in a short-term spatial memory task performed in the real world. Subjects were asked to play the Memory game (a.k.a. the Concentration game) without an...

Université de Fribourg

Phenotypic diversity and population growth in a fluctuating environment

Dombry, Clément ; Mazza, Christian ; Bansaye, Vincent

In: Advances in Applied Probability, 2011, vol. 43, no. 2, p. 375-398

Organisms adapt to fluctuating environments by regulating their dynamics, and by adjusting their phenotypes to environmental changes. We model population growth using multitype branching processes in random environments, where the offspring distribution of some organism having trait t ∈ T in environment e ∈ E is given by some (fixed) distribution...

Université de Fribourg

Nuclear factor I revealed as family of promoter binding transcription activators

Pjanic, Milos ; Pjanic, Petar ; Schmid, Christoph ; Ambrosini, Giovanna ; Gaussin, Armelle ; Plasari, Genta ; Mazza, Christian ; Bucher, Philipp ; Mermod, Nicolas

In: BMC Genomics, 2011, vol. 12, p. 181

Background: Multiplex experimental assays coupled to computational predictions are being increasingly employed for the simultaneous analysis of many specimens at the genome scale, which quickly generates very large amounts of data. However, inferring valuable biological information from the comparisons of very large genomic datasets still represents an enormous challenge.Results: As a study...

Université de Fribourg

Some remarks on Betti numbers of random polygon spaces

Dombry, Clément ; Mazza, Christian

In: Random Structures & Algorithms, 2010, vol. 37, no. 1, p. 67–84

Polygon spaces such as $ M_{\ell} = \{ (u_{1,\ldots,} u_{n})\; \epsilon \; S^{1}\times \ldots S^{1}, \sum \nolimits^{n}_{i=1}\;l_{i}u_{i} = 0 \}/SO(2) $, or the three-dimensional analogs Nℓ play an important rle in geometry and topology, and are also of interest in robotics where the li model the lengths of robot arms. When n is large, one can assume that each li is a positive real valued...

Université de Fribourg

Modeling food webs: exploring unexplained structure using latent traits

Rohr, Rudolf Philippe ; Scherer, Heike ; Kehrli, Patrik ; Mazza, Christian ; Bersier, Louis-Félix

In: The American Naturalist, 2010, vol. 176, no. 2, p. 170-177

Several stochastic models have tried to capture the architecture of food webs. This approach is interesting, but it is limited by the fact that different assumptions can yield similar results. To overcome this limitation, we develop a purely statistical approach. Body size in terms of an optimal ratio between prey and predator is used as explanatory variable. In 12 observed food webs, this model...

Université de Fribourg

Convergence and asymptotic variance of bootstrapped finite-time ruin probabilities with partly shifted risk processes

Loisel, Stéphane ; Mazza, Christian ; Rullière, Didier

In: Insurance: Mathematics and Economics, 2009, vol. 45, no. 3, p. 374-381

In the classical risk model, we prove the weak convergence of a sequence of empirical finite-time ruin probabilities. In an earlier paper (see Loisel et al., (2008)), we proved an equivalent result in the special case where the initial reserve is zero, and checked that numerically the general case seems to be true. In this paper, we prove the general case (with a nonnegative initial reserve),...

Université de Fribourg

Robustness analysis and convergence of empirical finite-time ruin probabilities and estimation risk solvency margin

Loisel, Stéphane ; Mazza, Christian ; Rullière, Didier

In: Insurance: Mathematics and Economics, 2008, vol. 42, no. 2, p. 746-762

We consider the classical risk model and carry out a sensitivity and robustness analysis of finite-time ruin probabilities. We provide algorithms to compute the related influence functions. We also prove the weak convergence of a sequence of empirical finite-time ruin probabilities starting from zero initial reserve toward a Gaussian random variable. We define the concepts of reliable finite-time...

Université de Fribourg

Statistical significance of quantitative PCR

Karlen, Yann ; McNair, Alan ; Perseguers, Sébastien ; Mazza, Christian ; Mermod, Nicolas

In: BMC Bioinformatics, 2007, vol. 8, p. 131

Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection and processing strategies have been described for the implementation of quantitative PCR. However, they can be experimentally cumbersome, their relative performances have not been evaluated systematically, and they...