In: Neural Development, 2012, vol. 7, p. 14
In Drosophila, most neurogenetic research is carried out in vivo. Mammalian research demonstrates that primary cell culture techniques provide a powerful model to address cell autonomous and non-autonomous processes outside their endogenous environment. We developed a cell culture system in Drosophila using wildtype and genetically manipulated primary neural tissue for long-term observations. We...
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In: JBIC Journal of Biological Inorganic Chemistry, 2011, vol. 16, no. 7, p. 1047-1056
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In: Developmental Biology, 2015, vol. 405, no. 2, p. 202–213
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In: Experimental Gerontology, 2006, vol. 42, no. 3, p. 247-251
The extension of life span by diet restriction in Drosophila has been argued to occur without limiting calories. Here we directly measure the calories assimilated by flies when maintained on full- and restricted-diets. We find that caloric intake is reduced on all diets that extend life span. Flies on low-yeast diet are long-lived and consume about half the calories of flies on high-yeast diets,...
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In: Nature, 2009, vol. 462, no. 24, p. 989-990
Dietary restriction promotes longevity but impairs fecundity in many organisms. When the amino acids in a diet are fine-tuned, however, lifespan can be increased without loss of fecundity — at least in fruitflies.
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In: BioMetals, 2011, vol. 24, no. 3, p. 445-453
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In: The Journal of Comparative Neurology, 2011, vol. 59, no. 17, p. 3415–3432
Whereas the “vertical” elements of the insect olfactory pathway, the olfactory receptor neurons and the projection neurons, have been studied in great detail, local interneurons providing “horizontal” connections in the antennal lobe were ignored for a long time. Recent studies in adult Drosophila demonstrate diverse roles for these neurons in the integration of odor information,...
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In: Chemical Senses, 2006, vol. 32, no. 1, p. 65-89
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In: Developmental Biology, 2011, p. -
The task of the visual system is to translate light into neuronal encoded information. This translation of photons into neuronal signals is achieved by photoreceptor neurons (PRs), specialized sensory neurons, located in the eye. Upon perception of light the PRs will send a signal to target neurons, which represent a first station of visual processing. Increasing complexity of visual processing...
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In: Population Ecology, 2010, vol. 52, no. 1, p. 15-25
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