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Université de Fribourg

Neural correlates of maladaptive pain behavior in chronic neck pain - a single case control fMRI study

Beinert, Konstantin ; Mouthon, Audrey ; Keller, Martin ; Mouthon, Michael ; Annoni, Jean-Marie ; Taube, Wolfgang

In: Pain Physician, 2017, vol. 20, no. 1, p. E115–E125

Chronic neck pain patients display functional impairments like decreased range of motion, decreased strength, and reduced sensorimotor function. In patients without structural damage, the reason for the persistence of pain is not well understood. Therefore, it is assumed that in chronic pain states, memory processes play an important role. We have now detected and tested a patient that might...

Université de Fribourg

Screening for language disorders in stroke: german validation of the language screening test (last)

Koenig-Bruhin, M. ; Vanbellingen, Tim ; Schumacher, Rahel ; Pflugshaupt, T. ; Annoni, Jean-Marie ; Müri, René M. ; Bohlhalter, Stephan ; Nyffeler, Thomas

In: Cerebrovascular Diseases Extra, 2016, vol. 6, no. 1, p. 27–31

Background: Screening of aphasia in acute stroke is crucial for directing patients to early language therapy. The Language Screening Test (LAST), originally developed in French, is a validated language screening test that allows detection of a language deficit within a few minutes. The aim of the present study was to develop and validate two parallel German versions of the LAST. Methods: The...

Université de Fribourg

The role of the cognitive control system in recovery from bilingual aphasia: a multiple single-case fMRI study

Radman, Narges ; Mouthon, Michael ; Pietro, Marie Di ; Gaytanidis, Chrisovalandou ; Leemann, Beatrice ; Abutalebi, Jubin ; Annoni, Jean-Marie

In: Neural Plasticity, 2016, vol. 2016, p. e8797086

Aphasia in bilingual patients is a therapeutic challenge since both languages can be impacted by the same lesion. Language control has been suggested to play an important role in the recovery of first (L1) and second (L2) language in bilingual aphasia following stroke. To test this hypothesis, we collected behavioral measures of language production (general aphasia evaluation and picture...

Université de Fribourg

Language specificity of lexical-phonological therapy in bilingual aphasia: A clinical and electrophysiological study

Radman, Narges ; Spierer, Lucas ; Laganaro, Marina ; Annoni, Jean-Marie ; Colombo, Françoise

In: Neuropsychological Rehabilitation, 2016, vol. 26, no. 4, p. 532–557

Based on findings for overlapping representations of bilingual people's first (L1) and second (L2) languages, unilingual therapies of bilingual aphasia have been proposed to benefit the untrained language. However, the generalisation patterns of intra- and cross-language and phonological therapy and their neural bases remain unclear. We tested whether the effects of an intensive...

Université de Fribourg

Partly segregated cortico-subcortical pathways support phonologic and semantic verbal fluency: A lesion study

Chouiter, Leila ; Holmberg, Josefina ; Manuel, Aurelie L. ; Colombo, Françoise ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Neuroscience, 2016, vol. 329, p. 275–283

Verbal fluency refers to the ability to generate as many words as possible in a limited time interval, without repetition and according to either a phonologic (each word begins with a given letter) or a semantic rule (each word belongs to a given semantic category). While current literature suggests the involvement of left fronto-temporal structures in fluency tasks, whether the same or...

Université de Fribourg

The modulation of reading strategies by language opacity in early bilinguals: an eye movement study

De León Rodríguez, Diego ; Buetler, C,, Karin A. ; Eggenberger, Noëmi ; Preisig, Basil C. ; Schumacher, Rahel ; Laganaro, Marina ; Nyffeler, Thomas ; Annoni, Jean-Marie ; Müri, René M.

In: Bilingualism: Language and Cognition, 2016, vol. 19, no. 3, p. 567–577

Converging evidences from eye movement experiments indicate that linguistic contexts influence reading strategies. However, the question of whether different linguistic contexts modulate eye movements during reading in the same bilingual individuals remains unresolved. We examined reading strategies in a transparent (German) and an opaque (French) language of early, highly proficient...

Université de Fribourg

Experience-based auditory predictions modulate brain activity to silence as do real sounds

Chouiter, Leila ; Tzovara, Athina ; Dieguez, Sebastian ; Annoni, Jean-Marie ; Magezi, David ; De Lucia, Marzia ; Spierer, Lucas

In: Journal of Cognitive Neuroscience, 2015, vol. 27, no. 10, p. 1968–1980

Interactions between stimuli's acoustic features and experience-based internal models of the environment enable listeners to compensate for the disruptions in auditory streams that are regularly encountered in noisy environments. However, whether auditory gaps are filled in predictively or restored a posteriori remains unclear. The current lack of positive statistical evidence that internal...

Université de Fribourg

Planning of spatially-oriented locomotion following focal brain damage in humans: A pilot study

Hicheur, Halim ; Boujon, Carole ; Wong, Cuebong ; Pham, Quang-Cuong ; Annoni, Jean-Marie ; Bihl, Titus

In: Behavioural Brain Research, 2016, vol. 301, p. 33–42

Motor impairments in human gait following stroke or focal brain damage are well documented. Here, we investigated whether stroke and/or focal brain damage also affect the navigational component of spatially oriented locomotion. Ten healthy adult participants and ten adult brain-damaged patients had to walk towards distant targets from different starting positions (with vision or blindfolded). No...

Université de Fribourg

Comprehension of co-speech gestures in aphasic patients: an eye movement study

Eggenberger, Noëmi ; Preisig, Basil C. ; Schumacher, Rahel ; Hopfner, Simone ; Vanbellingen, Tim ; Nyffeler, Thomas ; Gutbrod, Klemens ; Annoni, Jean-Marie ; Bohlhalter, Stephan ; Cazzoli, Dario ; Müri, René M.

In: PLOS ONE, 2016, vol. 11, no. 1, p. e0146583

Co-speech gestures are omnipresent and a crucial element of human interaction by facilitating language comprehension. However, it is unclear whether gestures also support language comprehension in aphasic patients. Using visual exploration behavior analysis, the present study aimed to investigate the influence of congruence between speech and co-speech gestures on comprehension in terms of...

Université de Fribourg

Balanced bilinguals favor lexical processing in their opaque language and conversion system in their shallow language

Buetler, Karin A. ; Rodríguez, Diego de León ; Laganaro, Marina ; Müri, René ; Nyffeler, Thomas ; Spierer, Lucas ; Annoni, Jean-Marie

In: Brain and Language, 2015, vol. 150, p. 166–176

Referred to as orthographic depth, the degree of consistency of grapheme/phoneme correspondences varies across languages from high in shallow orthographies to low in deep orthographies. The present study investigates the impact of orthographic depth on reading route by analyzing evoked potentials to words in a deep (French) and shallow (German) language presented to highly proficient bilinguals....