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12 results 1 2
Université de Fribourg

Comparison of cannabinoid concentrations in oral fluid and whole blood between occasional and regular cannabis smokers prior to and after smoking a cannabis joint

Fabritius, Marie ; Chtioui, Haithem ; Battistella, Giovanni ; Annoni, Jean Marie ; Dao, Kim ; Favrat, Bernard ; Fornari, Eleonora ; Lauer, Estelle ; Maeder, Philippe ; Giroud, Christian

In: Analytical and Bioanalytical Chemistry, 2013, vol. 405, no. 30, p. 9791–9803

A cross-over controlled administration study of smoked cannabis was carried out on occasional and heavy smokers. The participants smoked a joint (11 % Δ9-tetrahydrocannabinol (THC)) or a matching placebo on two different occasions. Whole blood (WB) and oral fluid (OF) samples were collected before and up to 3.5 h after smoking the joints. Pharmacokinetic analyses were obtained from these data....

Université de Fribourg

Weed or wheel! FMRI, behavioural, and toxicological investigations of how cannabis smoking affects skills necessary for driving

Battistella, Giovanni ; Fornari, Eleonora ; Thomas, Aurélien ; Mall, Jean-Frédéric ; Chtioui, Haithem ; Appenzeller, Monique ; Annoni, Jean-Marie ; Favrat, Bernard ; Maeder, Philippe ; Giroud, Christian

In: PLoS ONE, 2013, vol. 8, no. 1, p. e52545

Marijuana is the most widely used illicit drug, however its effects on cognitive functions underling safe driving remain mostly unexplored. Our goal was to evaluate the impact of cannabis on the driving ability of occasional smokers, by investigating changes in the brain network involved in a tracking task. The subject characteristics, the percentage of Δ9-Tetrahydrocannabinol in the joint, and...

12 results 1 2