Consortium of Swiss Academic Libraries

Rapid turnover of the recirculating lymphocyte pool in vivo

Young, Alan J. ; Hay, John B. ; Miyasaka, M.

In: International Immunology, 1995, vol. 7, no. 10, p. 1607-1615

Université de Fribourg

In breast cancer, a high ratio of tumour-infiltrating intraepithelial CD8+ to FoxP3+ cells is characteristic for the medullary subtype

Anz, David ; Eiber, Stephan ; Scholz, Christoph ; Endres, Stefan ; Kirchner, Thomas ; Bourquin, Carole ; Mayr, Doris

In: Histopathology, 2011, vol. 59, no. 5, p. 965–974

Aims: Medullary breast cancer (MBC) is a biologically distinct subtype of breast cancer characterized by prominent lymphocytic infiltrates and a favourable clinical outcome. Tumour-infiltrating CD8+ effector T cells may contribute to the good prognosis of this type of cancer; however, certain subtypes of lymphocyte, such as FoxP3+ regulatory T cells (Tregs), can also suppress antitumour...