Refine my results

Aggregation Stability of a Monoclonal Antibody During Downstream Processing

Arosio, Paolo ; Barolo, Giuliano ; Müller-Späth, Thomas ; Wu, Hua ; Morbidelli, Massimo

In: Pharmaceutical Research, 2011, vol. 28, no. 8, p. 1884-1894

Aggregation Mechanism of an IgG2 and two IgG1 Monoclonal Antibodies at low pH: From Oligomers to Larger Aggregates

Arosio, Paolo ; Rima, Simonetta ; Morbidelli, Massimo

In: Pharmaceutical Research, 2013, vol. 30, no. 3, p. 641-654

MsrR contributes to cell surface characteristics and virulence in Staphylococcus aureus

Hübscher, Judith ; McCallum, Nadine ; Sifri, Costi D. ; Majcherczyk, Paul A. ; Entenza, José M. ; Heusser, Roni ; Berger-Bächi, Brigitte ; Stutzmann Meier, Patricia

In: FEMS Microbiology Letters, 2009, vol. 295, no. 2, p. 251-260

Suppression of protein aggregation by chaperone modification of high molecular weight complexes

Labbadia, John ; Novoselov, Sergey S. ; Bett, John S. ; Weiss, Andreas ; Paganetti, Paolo ; Bates, Gillian P. ; Cheetham, Michael E.

In: Brain, 2012, vol. 135, no. 4, p. 1180-1196

Hold on to your friends: dedicated chaperones of ribosomal proteins

Pillet, Benjamin ; Mitterer, Valentin ; Kressler, Dieter ; Pertschy, Brigitte

In: BioEssays, 2017, vol. 39, no. 1, p. -

Eukaryotic ribosomes are assembled from their components, the ribosomal RNAs and ribosomal proteins, in a tremendously complex, multi-step process, which primarily takes place in the nuclear compartment. Therefore, most ribosomal proteins have to travel from the cytoplasm to their incorporation site on pre-ribosomes within the nucleus. However, due to their particular characteristics, such as...

Consensus of self-driven agents with avoidance of collisions

Peng, Liqian ; Zhao, Yang ; Tian, Baomei ; Zhang, Jue ; Wang, Bing-Hong ; Zhang, Hai-Tao ; Zhou, Tao

In: Physical Review E, 2009, vol. 79, no. 2, p. 026113

In recent years, many efforts have been addressed on collision avoidance of collectively moving agents. In this paper, we propose a modified version of the Vicsek model with adaptive speed, which can guarantee the absence of collisions. However, this strategy leads to an aggregated state with slowly moving agents. We therefore further add a certain repulsion, which results in both faster...

Analogy of the Coordination Chemistry of Alkaline Earth Metal and Lanthanide Ln²⁺ Ions: The Isostructural Zoo of Mixed Metal Cages [IM(OtBu)₄{Li(thf)}₄(OH)] (M=Ca, Sr, Ba, Eu), [MM′₆(OPh)₈(thf)₆] (M=Ca, Sr, Ba, Sm, Eu, M′=Li, Na), and their Derivatives with 1,2-Dimethoxyethane

Maudez, William ; Meuwly, Markus ; Fromm, Katharina M.

In: Chemistry - A European Journal, 2007, vol. 13, no. 29, p. 8302 - 8316

As previously shown, alkali and alkaline earth metal iodides in nonaqueous, aprotic solvents behave like transition metal halides, forming cis- and trans-dihalides with various neutral O-donor ligands. These compounds can be used as precursors for the synthesis of new mixed alkali/alkaline earth metal aggregates. We show here that Ln²⁺ ions form isostructural cluster compounds....

Characterization of the pores in hydrous ferric oxide aggregates formed by freezing and thawing

Hofmann, Annette ; Pelletier, Manuel ; Michot, Laurent ; Stradner, Anna ; Schurtenberger, Peter ; Kretzschmar, Ruben

In: Journal of Colloid and Interface Science, 2004, vol. 271, p. 163-173

Hydrous ferric oxides (HFO) are efficient sorbents for inorganic and organic pollutants and therefore have great potentials in environmental science and engineering applications. Freezing and thawing of HFO suspensions leads to the formation of dense HFO aggregates. It facilitates the handling and increases the drying rate of HFO. In this study, we used a combination of pycnometry, gas adsorption...