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Hormonal regulation of the humoral innate immune response in Drosophila melanogaster

Flatt, Thomas ; Heyland, Andreas ; Rus, Florentina ; Porpiglia, Ermelinda ; Sherlock, Chris ; Yamamoto, Rochele ; Garbuzov, Alina ; Palli, Subba R. ; Tatar, Marc ; Silverman, Neal

In: The Journal of Experimental Biology, 2008, vol. 21, no. 1, p. 2712-2724

Juvenile hormone (JH) and 20-hydroxy-ecdysone (20E) are highly versatile hormones, coordinating development, growth, reproduction and aging in insects. Pulses of 20E provide key signals for initiating developmental and physiological transitions, while JH promotes or inhibits these signals in a stage-specific manner. Previous evidence suggests that JH and 20E might modulate innate immunity,...

Immunogenetics of invasive aspergillosis

Lamoth, Frédéric ; Rubino, Ivana ; Bochud, Pierre-Yves

In: Medical Mycology, 2011, vol. 49, no. Supplement_1, p. S125-S136

Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice

Kobayashi, Toshihiko ; Takahashi, Koichiro ; Nagai, Yoshinori ; Shibata, Takuma ; Otani, Masako ; Izui, Shozo ; Akira, Shizuo ; Gotoh, Yoshiyuki ; Kiyono, Hiroshi ; Miyake, Kensuke

In: International Immunology, 2008, vol. 20, no. 7, p. 881-891

A long and winding road: defining the biological role and clinical importance of paraoxonases

James, Richard W.

In: Clinical Chemical Laboratory Medicine, 2006, vol. 44, no. 9, p. 1052-1059

The role of oxidative stress during inflammatory processes

Lugrin, Jérôme ; Rosenblatt-Velin, Nathalie ; Parapanov, Roumen ; Liaudet, Lucas

In: Biological Chemistry, 2014, vol. 395, no. 2, p. 203-230

TGFβ receptor II gene deletion in leucocytes prevents cerebral vasculitis in bacterial meningitis

Malipiero, Ursula ; Koedel, Uwe ; Pfister, Hans-Walter ; Levéen, Per ; Bürki, Kurt ; Reith, Walter ; Fontana, Adriano

In: Brain, 2006, vol. 129, no. 9, p. 2404-2415

PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant

Wójtowicz, Agnieszka ; Lecompte, T. Doco ; Bibert, Stephanie ; Manuel, Oriol ; Rüeger, Sina ; Berger, Christoph ; Boggian, Katia ; Cusini, Alexia ; Garzoni, Christian ; Hirsch, Hans ; Khanna, Nina ; Mueller, Nicolas J. ; Meylan, Pascal R. ; Pascual, Manuel ; van Delden, Christian ; Bochud, Pierre-Yves ; Achermann, Rita ; Aubert, John-David ; Baumann, Philippe ; Beldi, Guido ; Benden, Christian ; Berger, Christoph ; Binet, Isabelle ; Bochud, Pierre-Yves ; Boely, Elsa ; Bucher, Heiner ; Bühler, Leo ; Carell, Thierry ; Catana, Emmanuelle ; Chalandon, Yves ; de Geest, Sabina ; de Rougemont, Olivier ; Dickenmann, Michael ; Duchosal, Michel ; Fehr, Thomas ; Ferrari-Lacraz, Sylvie ; Garzoni, Christian ; Gasche, Yvan ; Soccal, Paola Gasche ; Giostra, Emiliano ; Golshayan, Déla ; Good, Daniel ; Hadaya, Karine ; Hess, Christoph ; Hillinger, Sven ; Hirsch, Hans H. ; Hofbauer, Günther ; Huynh-Do, Uyen ; Immer, Franz ; Klaghofer, Richard ; Koller, Michael ; Kuntzen, Thomas ; Laesser, Bettina ; Lehmann, Roger ; Lovis, Christian ; Manuel, Oriol ; Marti, Hans-Peter ; Martin, Pierre Yves ; Meylan, Pascal ; Mohacsi, Paul ; Morard, Isabelle ; Morel, Philippe ; Mueller, Ulrike ; Mueller, Nicolas J. ; Mueller-McKenna, Helen ; Müller, Thomas ; Müllhaupt, Beat ; Nadal, David ; Nair, Gayathri ; Pascual, Manuel ; Passweg, Jakob ; Ziegler, Chantal Piot ; Rick, Juliane ; Roosnek, Eddy ; Rosselet, Anne ; Rothlin, Silvia ; Ruschitzka, Frank ; Schanz, Urs ; Schaub, Stefan ; Seiler, Christian ; Semmo, Nasser ; Stampf, Susanne ; Steiger, Jürg ; Toso, Christian ; Tsinalis, Dimitri ; Van Delden, Christian ; Venetz, Jean-Pierre ; Villard, Jean ; Wick, Madeleine ; Wilhelm, Markus ; Yerly, Patrick ; Achermann, Rita ; Aubert, John-David ; Baumann, Philippe ; Beldi, Guido ; Benden, Christian ; Berger, Christoph ; Binet, Isabelle ; Bochud, Pierre-Yves ; Boely, Elsa ; Bucher, Heiner ; Bühler, Leo ; Carell, Thierry ; Catana, Emmanuelle ; Chalandon, Yves ; de Geest, Sabina ; de Rougemont, Olivier ; Dickenmann, Michael ; Duchosal, Michel ; Fehr, Thomas ; Ferrari-Lacraz, Sylvie ; Garzoni, Christian ; Gasche, Yvan ; Soccal, Paola Gasche ; Giostra, Emiliano ; Golshayan, Déla ; Good, Daniel ; Hadaya, Karine ; Hess, Christoph ; Hillinger, Sven ; Hirsch, Hans H. ; Hofbauer, Günther ; Huynh-Do, Uyen ; Immer, Franz ; Klaghofer, Richard ; Koller, Michael ; Kuntzen, Thomas ; Laesser, Bettina ; Lehmann, Roger ; Lovis, Christian ; Manuel, Oriol ; Marti, Hans-Peter ; Martin, Pierre Yves ; Meylan, Pascal ; Mohacsi, Paul ; Morard, Isabelle ; Morel, Philippe ; Mueller, Ulrike ; Mueller, Nicolas J. ; Mueller-McKenna, Helen ; Müller, Thomas ; Müllhaupt, Beat ; Nadal, David ; Nair, Gayathri ; Pascual, Manuel ; Passweg, Jakob ; Ziegler, Chantal Piot ; Rick, Juliane ; Roosnek, Eddy ; Rosselet, Anne ; Rothlin, Silvia ; Ruschitzka, Frank ; Schanz, Urs ; Schaub, Stefan ; Seiler, Christian ; Semmo, Nasser ; Stampf, Susanne ; Steiger, Jürg ; Toso, Christian ; Tsinalis, Dimitri ; Van Delden, Christian ; Venetz, Jean-Pierre ; Villard, Jean ; Wick, Madeleine ; Wilhelm, Markus ; Yerly, Patrick

In: Clinical Infectious Diseases, 2015, vol. 61, no. 4, p. 619-622

IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation

Wójtowicz, Agnieszka ; Gresnigt, Mark S. ; Lecompte, Thanh ; Bibert, Stephanie ; Manuel, Oriol ; Joosten, Leo A.B. ; Rüeger, Sina ; Berger, Christoph ; Boggian, Katia ; Cusini, Alexia ; Garzoni, Christian ; Hirsch, Hans H. ; Weisser, Maja ; Mueller, Nicolas J. ; Meylan, Pascal R. ; Steiger, Jürg ; Kutalik, Zoltan ; Pascual, Manuel ; van Delden, Christian ; van de Veerdonk, Frank L. ; Bochud, Pierre-Yves ; Binet, I. ; De Geest, S. ; van Delden, C. ; Hofbauer, G. F. K. ; Huynh-Do, U. ; Koller, M. T. ; Lovis, C. ; Manuel, O. ; Meylan, P. ; Mueller, N. J. ; Pascual, M. ; Schaub, S. ; Steiger, J. ; Binet, I. ; De Geest, S. ; van Delden, C. ; Hofbauer, G. F. K. ; Huynh-Do, U. ; Koller, M. T. ; Lovis, C. ; Manuel, O. ; Meylan, P. ; Mueller, N. J. ; Pascual, M. ; Schaub, S. ; Steiger, J.

In: The Journal of Infectious Diseases, 2015, vol. 211, no. 10, p. 1646-1657

The cuticle and plant defense to pathogens

Metraux, Jean-Pierre ; Serrano, Mario ; Torres, Martha ; Coluccia, Fania ; L’Haridon, Floriane

In: Frontiers in Plant Science, 2014, vol. 5, p. 274

The cuticle provides a physical barrier against water loss and protects against irradiation, xenobiotics and pathogens. Components of the cuticle are perceived by invading fungi and activate developmental processes during pathogenesis. In addition, cuticle alterations of various types induce a syndrome of reactions that often results in resistance to necrotrophs. This article reviews the current...

Systemic cancer immunotherapy with Toll-like receptor 7 agonists: Timing is everything

Hotz, Christian ; Bourquin, Carole

In: Oncoimmunology, 2012, vol. 1, no. 2, p. 227-228

Toll-like receptor (TLR) 7 agonists represent a promising strategy for the immunotherapy of cancer. We have recently investigated the influence of TLR tolerance on the efficacy of systemic tumor treatment with TLR7 ligands. We propose that considering the kinetics of receptor sensitivity highly improves the outcome of cancer immunotherapy.