Université de Fribourg

Dissemination of multiresistant Enterobacter cloacae isolates producing OXA-48 and CTX-M-15 in a Spanish hospital

Fernández, Javier ; Montero, Ignacio ; Martínez, Óscar ; Fleites, Ana ; Poirel, Laurent ; Nordmann, Patrice ; Rodicio, M. Rosario

In: International Journal of Antimicrobial Agents, 2015, vol. 46, no. 4, p. 469–474

Twenty-one multiresistant Enterobacter cloacae isolates producing OXA-48 (n = 10), CTX-M-15 (n = 7) or both (n = 4) β-lactamases were detected in a Spanish hospital during a 1-year period (June 2013 to June 2014). The isolates were also resistant to non-β-lactam antimicrobials, further complicating the therapeutic options. Genotyping of the isolates...

Université de Fribourg

Clonal distribution of multidrug-resistant Enterobacter cloacae

Girlich, Delphine ; Poirel, Laurent ; Nordmann, Patrice

In: Diagnostic Microbiology and Infectious Disease, 2015, vol. 81, no. 4, p. 264–268

A multilocus sequence typing (MLST) scheme including 7 housekeeping genes was used to evaluate whether the current spread of multidrug-resistant Enterobacter cloacae isolates worldwide might be associated to specific successful clones. Fifty E. cloacae clinical isolates of worldwide origin, with various β-lactamase content, and recovered at different periods of time were studied. Forty-four...