Consortium of Swiss Academic Libraries

Cell cycle control and cancer

Wagner, Hans

In: The Indian Journal of Pediatrics, 1998, vol. 65, no. 6, p. 805-814

Consortium of Swiss Academic Libraries

The CDK inhibitors in cancer research and therapy

Cicenas, Jonas ; Valius, Mindaugas

In: Journal of Cancer Research and Clinical Oncology, 2011, vol. 137, no. 10, p. 1409-1418

Université de Fribourg

A dual epimorphic and compensatory mode of heart regeneration in zebrafish

Sallin, Pauline ; Preux Charles, Anne-Sophie de ; Duruz, Vincent ; Pfefferli, Catherine ; Jaźwińska, Anna

In: Developmental Biology, 2015, vol. 399, no. 1, p. 27–40

Zebrafish heart regeneration relies on the capacity of cardiomyocytes to proliferate upon injury. To understand the principles of this process after cryoinjury-induced myocardial infarction, we established a spatio-temporal map of mitotic cardiomyocytes and their differentiation dynamics. Immunodetection of phosphohistone H3 and embryonic ventricular heavy chain myosin highlighted two distinct...

Université de Fribourg

The CDK inhibitors in cancer research and therapy

Cicenas, Jonas ; Valius, Mindaugas

In: Journal Of Cancer Research and Clinical Oncology, 2011, vol. 137, no. 10, p. 1409-1418

Chemical compounds that interfere with an enzymatic function of kinases are useful for gaining insight into the complicated biochemical processes in mammalian cells. Cyclin-dependent kinases (CDK) play an essential role in the control of the cell cycle and/or proliferation. These kinases as well as their regulators are frequently deregulated in different human tumors. Aberrations in CDK...