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Microbiological tests to predict treatment outcome in experimental device-related infections due to Staphylococcus aureus

Zimmerli, Werner ; Frei, Reno ; Windmer, Andreas F. ; Rajacic, Zarko

In: Journal of Antimicrobial Chemotherapy, 1994, vol. 33, no. 5, p. 959-967

Penetration of rifampicin into the brain tissue and cerebral extracellular space of rats

Mindermann, Thomas ; Landolt, Hans ; Zimmerli, Werner ; Rajacic, Zarko ; Gratzl, Otmar

In: Journal of Antimicrobial Chemotherapy, 1993, vol. 31, no. 5, p. 731-737

Immune Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation and Association With Occurrence and Outcome of Invasive Aspergillosis

Stuehler, Claudia ; Kuenzli, Esther ; Jaeger, Veronika K. ; Baettig, Veronika ; Ferracin, Fabrizia ; Rajacic, Zarko ; Kaiser, Deborah ; Bernardini, Claudia ; Forrer, Pascal ; Weisser, Maja ; Elzi, Luigia ; Battegay, Manuel ; Halter, Joerg ; Passweg, Jakob ; Khanna, Nina

In: The Journal of Infectious Diseases, 2015, vol. 212, no. 6, p. 959-967

Preventing implant-associated infections by silver coating

Kuehl, Richard ; Brunetto, Priscilla S. ; Woischnig, Anne-Kathrin ; Varisco, Massimo ; Rajacic, Zarko ; Vosbeck, Juerg ; Terracciano, Luigi ; Fromm, Katharina M. ; Khanna, Nina

In: Antimicrobial Agents and Chemotherapy, 2016, p. AAC.02934–15

Implant-associated infections (IAI) are a dreaded complication mainly caused by biofilm-forming staphylococci. Implant surfaces preventing microbial colonization would be desirable. We examined the preventive effect of a silver-coated titanium aluminium niobium (TiAlNb) alloy. The surface elicited a strong, inoculum-dependent activity against Staphylococcus (S.) epidermidis and S. aureus in an...

Development of a polystyrene sulfonate/silver nanocomposite with self-healing properties for biomaterial applications

Girard, Jérôme ; Brunetto, Priscilla S. ; Braissant, Olivier ; Rajacic, Zarko ; Khanna, Nina ; Landmann, Regine ; Daniels, Alma U. ; Fromm, Katharina M.

In: Comptes Rendus Chimie, 2013, vol. 16, no. 6, p. 550–556

A silver polystyrene sulfonate polyelectrolyte was synthesized, showing a spontaneous reduction of silver ions to silver nanoparticles over a period of approximately 1 month. A follow-up of the nanoparticle formation via scanning electron microscopy (SEM) reveals migration of the nanoparticles towards the cracks of the polymer over time, leading to a self-healing process of the nanocomposite....

Rings, chains and helices: new antimicrobial silver coordination compounds with (iso-)nicotinic acid derivatives

Chevrier, Inès ; Sagué, Jorge L. ; Brunetto, Priscilla S. ; Khanna, Nina ; Rajacic, Zarko ; Fromm, Katharina M.

In: Dalton Transactions, 2013, vol. 42, no. 1, p. 217-231

Complexes with silver ions have great potential for applications in medicine. Appropriate bidentate ligands, binding to silver ions, are able to generate coordination polymers as well as molecular entities as a function of ligand flexibility, conformation and length. Here we present the continuation of our previous studies in this field with ligands based on oligomers of polyethylene glycol,...