Refine my results

Xenacoelomorpha survey reveals that all 11 animal homeobox gene classes were present in the first bilaterians

Brauchle, Michael ; Bilican, Adem ; Eyer, Claudia ; Bailly, Xavier ; Martínez, Pedro ; Ladurner, Peter ; Bruggmann, Rémy ; Sprecher, Simon G.

In: Genome Biology and Evolution, 2018, vol. 10, no. 9, p. 2205–2217

Homeodomain transcription factors are involved in many developmental processes across animals and have been linked to body plan evolution. Detailed classifications of these proteins identified 11 distinct classes of homeodomain proteins in animal genomes, each harboring specific sequence composition and protein domains. Although humans contain the full set of classes, Drosophila melanogaster...

Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster

Widmer, Yves F. ; Bilican, Adem ; Bruggmann, Rémy ; Sprecher, Simon G.

In: Genetics, 2018, vol. 209, no. 4, p. 1167–1181

Memory formation is achieved by genetically tightly controlled molecular pathways that result in a change of synaptic strength and synapse organization. While for short- term memory traces, rapidly acting biochemical pathways are in place, the formation of long-lasting memories requires changes in the transcriptional program of a cell. Although many genes involved in learning and memory...

Mushroom body-specific profiling of gene expression identifies regulators of long-term memory in Drosophila

Widmer, Yves F. ; Bilican, Adem ; Bruggmann, Rémy ; Sprecher, Simon G.

Memory formation is achieved by genetically tightly controlled molecular pathways that result in a change of synaptic strength and synapse organization. While for short- term memory traces rapidly acting biochemical pathways are in place, the formation of long-lasting memories requires changes in the transcriptional program of a cell. Although many genes involved in learning and memory...