Université de Fribourg

FRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK

Meunier, Danièle ; Findlay, Jacqueline ; Doumith, Michel ; Godoy, Daniel ; Perry, Claire ; Pike, Rachel ; Gronthoud, Firza ; Shryane, Theresa ; Poirel, Laurent ; Welfare, William ; Woodford, Neil ; Hopkins, Katie L.

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 9, p. 2478–2482

Objectives: Detection of rarer carbapenemases is challenging, as it requires molecular assays with comprehensive coverage or the use of phenotypic methods for the detection of carbapenemase activity. We describe a new class A carbapenemase, FRI-2, in an Enterobacter cloacae complex isolate following implementation of an in- house multiplex PCR for the detection of ‘rare’ class A...

Université de Fribourg

Occurrence of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE): a prospective, multinational study

Grundmann, Hajo ; Glasner, Corinna ; Albiger, Barbara ; Aanensen, David M. ; Tomlinson, Chris T. ; Andrasević, Arjana Tambić ; Cantón, Rafael ; Carmeli, Yehuda ; Friedrich, Alexander W. ; Giske, Christian G. ; Glupczynski, Youri ; Gniadkowski, Marek ; Livermore, David M. ; Nordmann, Patrice ; Poirel, Laurent ; Rossolini, Gian M. ; Seifert, Harald ; Vatopoulos, Alkiviadis ; Walsh, Timothy ; Woodford, Neil ; Monnet, Dominique L. ; the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) Working Group

In: The Lancet Infectious Diseases, 2017, vol. 17, no. 2, p. 153–163

Gaps in the diagnostic capacity and heterogeneity of national surveillance and reporting standards in Europe make it difficult to contain carbapenemase-producing Enterobacteriaceae. We report the development of a consistent sampling framework and the results of the first structured survey on the occurrence of carbapenemase- producing Klebsiella pneumoniae and Escherichia coli in European...