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Cross-resistance to human cationic antimicrobial peptides and to polymyxins mediated by the plasmid-encoded MCR-1?

Dobias, Jan ; Poirel, Laurent ; Nordmann, Patrice

In: Clinical Microbiology and Infection, 2017, p. -

To evaluate whether acquired resistance to cationic antimicrobial peptides (CAMP) group molecules, being normal components of the human immune system, may select co-resistance to antibiotic peptides such as polymyxins, considering they share the same mechanism of action. We aimed to evaluate strains producing the recently identified plasmid-encoded polymyxin resistance determinant MCR-1,...

Plasmid-mediated colistin resistance: an additional antibiotic resistance menace

Nordmann, Patrice ; Poirel, Laurent

In: Clinical Microbiology and Infection, 2016, vol. 22, no. 5, p. 398–400