Université de Fribourg

Regulation of ABCB1/PGP1-catalysed auxin transport by linker phosphorylation

Henrichs, Sina ; Wang, Bangjun ; Fukao, Yoichiro ; Zhu, Jinsheng ; Charrier, Laurence ; Bailly, Aurélien ; Oehring, Sophie C ; Linnert, Miriam ; Weiwad, Matthias ; Endler, Anne ; Nanni, Paolo ; Pollmann, Stephan ; Mancuso, Stefano ; Schulz, Alexander ; Geisler, Markus

In: The EMBO Journal, 2012, p. -

Polar transport of the plant hormone auxin is controlled by PIN- and ABCB/PGP-efflux catalysts. PIN polarity is regulated by the AGC protein kinase, PINOID (PID), while ABCB activity was shown to be dependent on interaction with the FKBP42, TWISTED DWARF1 (TWD1). Using co-immunoprecipitation (co-IP) and shotgun LC–MS/MS analysis, we identified PID as a valid partner in the interaction with...