Università della Svizzera italiana

Leukocyte tracking database, a collection of immune cell tracks from intravital 2-photon microscopy videos

Pizzagalli, Diego Ulisse ; Farsakoglu, Yagmur ; Palomino-Segura, Miguel ; Palladino, Elisa ; Sintes, Jordi ; Marangoni, Francesco ; Mempel, Thorsten R. ; Koh, Wan Hon ; Murooka, Thomas T. ; Thelen, Flavian ; Stein, Jens V. ; Pozzi, Giuseppe ; Marcus Thelen ; Krause, Rolf ; Gonzalez, Santiago Fernandez

In: Scientific data, 2018, vol. 5, p. 180129

Recent advances in intravital video microscopy have allowed the visualization of leukocyte behavior in vivo, revealing unprecedented spatiotemporal dynamics of immune cell interaction. However, state-of-the-art software and methods for automatically measuring cell migration exhibit limitations in tracking the position of leukocytes over time. Challenges arise both from the complex migration...