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Université de Neuchâtel

Biochemical markers of fatal hypothermia

Palmiere, Cristian ; Bardy, Daniel ; Letovanec, Igor ; Mangin, Patrice ; Augsburger, Marc ; Ventura, Francesco ; Iglesias, Katia ; Werner, Dominique

In: Forensic Science International, 2013, vol. 226, no. 1-3, p. 54-61

The aim of this study was to investigate the usefulness of postmortem biochemical investigations in the diagnosis of fatal hypothermia. 10 cases of fatal hypothermia and 30 control cases were selected. A series of biochemical parameters, such as glucose, acetone, 3-beta-hydroxybutyrate, isopropyl alcohol, free fatty acids, adrenaline, growth hormone, adrenocorticotropic hormone,...

Université de Neuchâtel

Diagnostic value of lipopolysaccharide-binding protein and procalcitonin for sepsis diagnosis in forensic pathology

Augsburger, Marc ; Iglesias, Katia ; Bardy, Daniel ; Mangin, Patrice ; Palmiere, Cristian

In: International Journal of Legal Medicine, 2013, vol. 127, no. 2, p. 427-435

The aims of this study were twofold. The first was to investigate the diagnostic performance of two biochemical markers, procalcitonin (PCT) and lipopolysaccharide-binding protein (LBP), considering each individually and then combined, for the postmortem diagnosis of sepsis. We also tested the usefulness of pericardial fluid for postmortem LBP determination. Two study groups were formed, a...

Université de Neuchâtel

Assessment of adult formulas for glomerular filtration rate estimation in children

Chehade, Hassib ; Girardin, Eric ; Iglesias, Katia ; Ramseyer, Pascal ; Frey, Peter ; Bardy, Daniel ; Mosig, Dolores ; Cachat, Francois

In: Pediatric Nephrology, 2013, vol. 28, no. 1, p. 105-114

Background Estimated glomerular filtration rate (eGFR) is an important diagnostic instrument in clinical practice. The National Kidney Foundation-Kidney Disease Quality Initiative (NKF–KDOQI) guidelines do not recommend using formulas developed for adults to estimate GFR in children; however, studies confirming these recommendations are scarce. The aim of our study was to evaluate the...

Université de Fribourg

Circadian variations of ischemic burden among patients with myocardial infarction undergoing primary percutaneous coronary intervention

Fournier, Stephane ; Eeckhout, Eric ; Mangiacapra, Fabio ; Trana, Catalina ; Lauriers, Nathalie ; Beggah, Ahmed T. ; Monney, Pierre ; Cook, Stéphane ; Bardy, Daniel ; Vogt, Pierre ; Muller, Olivier

In: American Heart Journal, 2012, vol. 163, no. 2, p. 208–213

Background: Several parameters of cardiovascular physiology and pathophysiology exhibit circadian rhythms. Recently, a relation between infarct size and the time of day at which it occurs has been suggested in experimental models of myocardial infarction. The aim of this study is to investigate whether circadian rhythms could cause differences in ischemic burden in patients with ST-elevation...