Université de Fribourg

Sequencing and characterizing the genome of Estrella lausannensis as an undergraduate project: training students and biological insights

Bertelli, Claire ; Aeby, Sébastien ; Chassot, Bérénice ; Clulow, James ; Hilfiker, Olivier ; Rappo, Samuel ; Ritzmann, Sébastien ; Schumacher, Paolo ; Terrettaz, Céline ; Benaglio, Paola ; Falquet, Laurent ; Farinelli, Laurent ; Gharib, Walid H. ; Goesmann, Alexander ; Harshman, Keith ; Linke, Burkhard ; Miyazaki, Ryo ; Rivolta, Carlo ; Robinson-Rechavi, Marc ; Meer, Jan Roelof van der ; Greub, Gilbert

In: Frontiers in Microbiology, 2015, vol. 6, p. 101

With the widespread availability of high-throughput sequencing technologies, sequencing projects have become pervasive in the molecular life sciences. The huge bulk of data generated daily must be analyzed further by biologists with skills in bioinformatics and by “embedded bioinformaticians,” i.e., bioinformaticians integrated in wet lab research groups. Thus, students interested in...

Université de Fribourg

Comparative genome analysis of Pseudomonas knackmussii B13, the first bacterium known to degrade chloroaromatic compounds

Miyazaki, Ryo ; Bertelli, Claire ; Benaglio, Paola ; Canton, Jonas ; Coi, Nicoló De ; Gharib, Walid H. ; Gjoksi, Bebeka ; Goesmann, Alexander ; Greub, Gilbert ; Harshman, Keith ; Linke, Burkhard ; Mikulic, Josip ; Mueller, Linda ; Nicolas, Damien ; Robinson-Rechavi, Marc ; Rivolta, Carlo ; Roggo, Clémence ; Roy, Shantanu ; Sentchilo, Vladimir ; Siebenthal, Alexandra Von ; Falquet, Laurent ; Meer, Jan Roelof van der

In: Environmental Microbiology, 2014, p. -

Pseudomonas knackmussii B13 was the first strain to be isolated in 1974 that could degrade chlorinated aromatic hydrocarbons. This discovery was the prologue for subsequent characterization of numerous bacterial metabolic pathways, for genetic and biochemical studies, and which spurred ideas for pollutant bioremediation. In this study, we determined the complete genome sequence of B13 using...