Refine my results

Document type

Specific Collection

Language

Université de Fribourg

Insertion of Nanoparticle Clusters into Vesicle Bilayers

Bonnaud, Cécile ; Monnier, Christophe A. ; Demurtas, Davide ; Jud, Corinne ; Vanhecke, Dimitri ; Montet, Xavier ; Hovius, Ruud ; Lattuada, Marco ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: ACS Nano, 2014, vol. 8, no. 4, p. 3451–3460

A major contemporary concern in developing effective liposome–nanoparticle hybrids is the present inclusion size limitation of nanoparticles between vesicle bilayers, which is considered to be around 6.5 nm in diameter. In this article, we present experimental observations backed by theoretical considerations which show that greater structures can be incorporated within vesicle membranes by...

Université de Fribourg

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

Garrido-Urbani, Sarah ; Jemelin, Stephane ; Deffert, Christine ; Carnesecchi, Stéphanie ; Basset, Olivier ; Szyndralewiez, Cédric ; Heitz, Freddy ; Page, Patrick ; Montet, Xavier ; Michalik, Liliane ; Arbiser, Jack ; Rüegg, Curzio ; Krause, Karl Heinz ; Imhof, Beat A.

In: PLoS ONE, 2011, vol. 6, no. 2, p. e14665

Reactive oxygen species, ROS, are regulators of endothelial cell migration, proliferation and survival, events critically involved in angiogenesis. Different isoforms of ROS-generating NOX enzymes are expressed in the vasculature and provide distinct signaling cues through differential localization and activation. We show that mice deficient in NOX1, but not NOX2 or NOX4, have impaired...