Université de Fribourg

Plasma-functionalized electrospun matrix for biograft development and cardiac function stabilization

Guex, A.G. ; Frobert, A. ; Valentin, Jeremy ; Fortunato, G. ; Hegemann, D. ; Cook, Stéphane ; Carrel, T.P. ; Tevaearai, H.T. ; Giraud, Marie-Noelle

In: Acta Biomaterialia, 2014, vol. 10, no. 7, p. 2996–3006

Cardiac tissue engineering approaches can deliver large numbers of cells to the damaged myocardium and have thus increasingly been considered as a possible curative treatment to counteract the high prevalence of progressive heart failure after myocardial infarction (MI). Optimal scaffold architecture and mechanical and chemical properties, as well as immune- and bio-compatibility, need to be...