Université de Neuchâtel

Enhancement of Cytotoxicity by Combining Pyrenyl-Dendrimers and Arene Ruthenium Metallacages

Pitto-Barry, Anaïs ; Zava, Olivier ; Dyson, Paul J ; Deschenaux, Robert ; Therrien, Bruno

In: Inorganic Chemistry, 2012, vol. 51, no. 13, p. 7119-7124

Three generations of pyrenyl bis-MPA dendrimers with two different end-groups, acetonide (pyrGn) or alcohol (pyrGn-OH) (n = 1–3), were synthesized, and the pyrenyl group of the dendritic molecules was encapsulated in the arene ruthenium metallacages, [Ru6(p-cymene) 6 (OO∩OO)3(tpt)2]6+ (OO∩OO =...

Université de Neuchâtel

Designing Supramolecular Liquid-Crystalline Hybrids from Pyrenyl-Containing Dendrimers and Arene Ruthenium Metallacycles

Pitto-Barry, Anaïs ; Barry, Nicolas P. E ; Russo, Virginie ; Heinrich, Benoît ; Donnio, Bertrand ; Therrien, Bruno ; Deschenaux, Robert

In: Journal of the American Chemical Society, 2014, vol. 136, no. 50, p. 17616-17625

The association of the arene ruthenium metallacycle [Ru4(p- cymene)4(bpe)2(donq)2][DOS]4 (bpe = 1,2- bis(4-pyridyl)ethylene, donq = 5,8-dioxydo-1,4-naphtoquinonato, DOS = dodecyl sulfate) with pyrenyl-functionalized poly(arylester) dendrimers bearing cyanobiphenyl end- groups is reported. The supramolecular dendritic systems display...

Université de Neuchâtel

Propriétés mésomorphes ou biologiques d'assemblages dendritiques et métallodendritiques

Pitto-Barry, Anaïs ; Deschenaux, Robert (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2012 ; 2256.

The aim of this thesis is to combine metals and dendrimers to obtain mesomorphic or biological properties. The design of metamaterials from gold nanoparticles is still a challenge as the spatial organisation is difficult to control. Thus, the combination of gold nanoparticles with liquid-crystalline dendrimers is a way to explore the organisation of such systems in mesophases. We...

Université de Neuchâtel

Encapsulation of Pyrene-Functionalized Poly(benzyl ether) Dendrons into a Water-Soluble Organometallic Cage

Pitto-Barry, Anaïs ; Barry, Nicolas P. E. ; Zava, Olivier ; Deschenaux, Robert ; Therrien, Bruno

In: Chemistry – An Asian Journal, 2011, vol. 6, no. 6, p. 1595-1603

Two generations of lipophilic pyrenyl functionalized poly(benzyl ether) dendrimers (P1 and P2) have been synthesized. The thermal properties of the two functionalized dendrimers have been investigated, and the pyrenyl group of the dendritic molecules encapsulated in the arene–ruthenium metalla-cage,...

Université de Neuchâtel

Double Targeting of Tumours with Pyrenyl-Modified Dendrimers Encapsulated in an Arene–Ruthenium Metallaprism

Pitto-Barry, Anaïs ; Barry, Nicolas P. E. ; Zava, Olivier ; Deschenaux, Robert ; Dyson, Paul J. ; Therrien, Bruno

In: Chemistry – A European Journal, 2011, vol. 17, no. 6, p. 1966-1971

The self-assembly of 2,4,6-tris(pyridin-4-yl)-1,3,5-triazine (tpt) triangular panels with p-cymene–ruthenium building blocks and 5,8-dioxido-1,4-naphthoquinonato (donq) bridges, in the presence of pyrenyl-containing dendrimers of different generations (P0, P1 and P2), affords the triangular prismatic host–guest compounds...