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    Université de Fribourg

    Colistin resistance in Parisian inpatient faecal Escherichia coli as the result of two distinct evolutionary pathways

    Bourrel, Anne Sophie ; Poirel, Laurent ; Royer, Guilhem ; Darty, Mélanie ; Vuillemin, Xavier ; Kieffer, Nicolas ; Clermont, Olivier ; Denamur, Erick ; Nordmann, Patrice ; Decousser, Jean-Winoc ; The IAME Resistance Group

    In: Journal of Antimicrobial Chemotherapy, 2019, vol. 74, no. 6, p. 1521–1530

    Beyond plasmid-encoded resistance (mcr genes) prevalence in strain collections, large epidemiological studies to estimate the human burden of colistin-resistant Escherichia coli gut carriage are lacking.Objectives: To evaluate the prevalence of colistin-resistant E. coli carriage in inpatients and decipher the molecular support of resistance and the genetic background of the strains.Methods:...

    Université de Fribourg

    Are animals a source of Stenotrophomonas maltophilia in human infections? Contributions of a nationwide molecular study

    Jayol, Aurélie ; Corlouer, Camille ; Haenni, Marisa ; Darty, Mélanie ; Maillard, Karine ; Desroches, Marine ; Lamy, Brigitte ; Jumas-Bilak, Estelle ; Madec, Jean-Yves ; Decousser, Jean-Winoc

    In: European Journal of Clinical Microbiology & Infectious Diseases, 2018, p. 1–7

    Stenotrophomonas maltophilia (Sm) is an archetypal environmental opportunistic bacterium responsible for health care-associated infections. The role of animals in human Sm infections is unknown. This study aims to reveal the genetic and phylogenetic relationships between pathogenic strains of Sm, both animal and human, and identify a putative role for animals as a reservoir in human...

    2 results 1