Université de Fribourg

Partly segregated cortico-subcortical pathways support phonologic and semantic verbal fluency: A lesion study

Chouiter, Leila ; Holmberg, Josefina ; Manuel, Aurelie L. ; Colombo, Françoise ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Neuroscience, 2016, vol. 329, p. 275–283

Verbal fluency refers to the ability to generate as many words as possible in a limited time interval, without repetition and according to either a phonologic (each word begins with a given letter) or a semantic rule (each word belongs to a given semantic category). While current literature suggests the involvement of left fronto-temporal structures in fluency tasks, whether the same or...

Université de Fribourg

Contributions of pitch and bandwidth to sound-induced enhancement of visual cortex excitability in humans

Spierer, Lucas ; Manuel, Aurelie L. ; Bueti, Domenica ; Murray, Micah M.

In: Cortex, 2014, vol. 49, no. 10, p. 2728–2734

Multisensory interactions have been documented within low-level, even primary, cortices and at early post-stimulus latencies. These effects are in turn linked to behavioral and perceptual modulations. In humans, visual cortex excitability, as measured by transcranial magnetic stimulation (TMS) induced phosphenes, can be reliably enhanced by the co-presentation of sounds. This enhancement occurs...

Université de Fribourg

Plastic modifications within inhibitory control networks induced by practicing a stop-signal task: an electrical neuroimaging study

Manuel, Aurelie L. ; Bernasconi, Fosco ; Spierer, Lucas

In: Cortex, 2012, p. -

Inhibitory control refers to our ability to suppress ongoing motor, affective or cognitive processes and mostly depends on a fronto–basal brain network. Inhibitory control deficits participate in the emergence of several prominent psychiatric conditions, including attention deficit/hyperactivity disorder or addiction. The rehabilitation of these pathologies might therefore benefit from...

Université de Fribourg

inter- and intrahemispheric dissociations in ideomotor apraxia : a large-Scale lesion–symptom mapping study in subacute brain-damaged patients

Manuel, Aurelie L. ; Radman, Narges ; Mesot, Delphine ; Chouiter, Leila ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Cerebral Cortex, 2012, vol. 23, no. 12, p. 2781-2789

Pantomimes of object use require accurate representations of movements and a selection of the most task-relevant gestures. Prominent models of praxis, corroborated by functional neuroimaging studies, predict a critical role for left parietal cortices in pantomime and advance that these areas store representations of tool use. In contrast, lesion data points to the involvement of left inferior...

Université de Fribourg

Noise in brain activity engenders perception and influences discrimination sensitivity

Bernasconi, Fosco ; De Lucia, Marzia ; Tzovara, Athina ; Manuel, Aurelie L. ; Murray, Micah M. ; Spierer, Lucas

In: The Journal of Neuroscience, 2011, vol. 31, no. 49, p. 17971-17981

Behavioral and brain responses to identical stimuli can vary with experimental and task parameters, including the context of stimulus presentation or attention. More surprisingly, computational models suggest that noise-related random fluctuations in brain responses to stimuli would alone be sufficient to engender perceptual differences between physically identical stimuli. In two experiments...