Université de Fribourg

Interaction of the hydrogen sulfide system with the oxytocin system in the injured mouse heart

Merz, Tamara ; Lukaschewski, Britta ; Wigger, Daniela ; Rupprecht, Aileen ; Wepler, Martin ; Gröger, Michael ; Hartmann, Clair ; Whiteman, Matthew ; Szabo, Csaba ; Wang, Rui ; Waller, Christiane ; Radermacher, Peter ; McCook, Oscar

In: Intensive Care Medicine Experimental, 2018, vol. 6, no. 1, p. 41

Both the hydrogen sulfide/cystathionine-γ-lyase (H2S/CSE) and oxytocin/oxytocin receptor (OT/OTR) systems have been reported to be cardioprotective. H2S can stimulate OT release, thereby affecting blood volume and pressure regulation. Systemic hyper-inflammation after blunt chest trauma is enhanced in cigarette smoke (CS)-exposed CSE−/− mice compared to wildtype (WT). CS increases...

Université de Fribourg

Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis

Merz, Tamara ; Wepler, Martin ; Nußbaum, Benedikt ; Vogt, Josef ; Calzia, Enrico ; Wang, Rui ; Szabo, Csaba ; Radermacher, Peter ; McCook, Oscar

In: Intensive Care Medicine Experimental, 2018, vol. 6, no. 1, p. 43

Sepsis is associated with disturbed glucose metabolism and reduced mitochondrial activity and biogenesis, ultimately leading to multiple organ dysfunction, e.g., acute kidney injury (AKI). Cystathionine-γ-lyase (CSE), the major cardiovascular source of endogenous H2S release, is implicated in the regulation of glucose metabolism and mitochondrial activity through a PGC1α-dependent...

Consortium of Swiss Academic Libraries

Evolution of the solvent polarity in an electrospray plume

Wang, Rui ; Zenobi, Renato

In: Journal of the American Society for Mass Spectrometry, 2010, vol. 21, no. 3, p. 378-385

Université de Fribourg

Biological control opportunities of ragweed are predicted to decrease with climate change in East Asia

Sun, Yan ; Zhou, Zhongshi ; Wang, Rui ; Müller-Schärer, Heinz

In: Biodiversity Science, 2017, vol. 25, no. 12, p. 1285-1294

The control of invasive alien plants (IAP) that jeopardize our ecosystems and economy constitutes a significant challenge for natural resource management. Classical biological control referring to the introduction of specialist antagonists from the native range has proven to be a highly cost-effective management tool against IAP. A critical issue in biological control research is to guide...