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Università della Svizzera italiana

Posterior reversible leukoencephalopathy syndrome associated with acute postinfectious glomerulonephritis : systematic review

Orlando, Corinne ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Goeggel Simonetti, Barbara ; Lava, Sebastiano A. G. ; Wyttenbach, Rolf ; Bianchetti, Mario G. ; Cristallo Lacalamita, Marirosa

In: Pediatric nephrology, 2021, p. 9

Background Kidney diseases are a recognized cause of posterior reversible leukoencephalopathy syndrome, usually abbreviated as PRES. The purpose of this review was to systematically address the association between acute postinfectious glomerulonephritis and PRES. Methods We performed a systematic review of the literature on acute postinfectious glomerulonephritis associated with PRES. The...

Università della Svizzera italiana

Magnesium metabolism in chronic alcohol-use disorder : meta-analysis and systematic review

Vanoni, Flora O. ; Milani, Gregorio P. ; Agostoni, Carlo ; Treglia, Giorgio ; Faré, Pietro B. ; Camozzi, Pietro ; Lava, Sebastiano A. G. ; Bianchetti, Mario G. ; Janett, Simone

In: Nutrients, 2021, vol. 13, no. 6, p. 11

Chronic alcohol-use disorder has been imputed as a possible cause of dietary magnesium depletion. The purpose of this study was to assess the prevalence of hypomagnesemia in chronic alcohol-use disorder, and to provide information on intracellular magnesium and on its renal handling. We carried out a structured literature search up to November 2020, which returned 2719 potentially relevant...

Università della Svizzera italiana

Vitamin D status in adolescents during COVID-19 pandemic : a cross-sectional comparative study

Meoli, Martina ; Muggli, Franco ; Lava, Sebastiano A. G. ; Bianchetti, Mario G. ; Agostoni, Carlo ; Kocher, Claudine ; Bührer, Thomas W. ; Ciliberti, Letizia ; Simonetti, Giacomo D. ; Milani, Gregorio P.

In: Nutrients, 2021, vol. 13, no. 5, p. 7

Vitamin D has been claimed to be effective in the response to infections, including the respiratory syndrome coronavirus 2 (SARS-CoV-2). It is supposed that lockdown measures and fear of SARS-CoV-2 infection might reduce vitamin D levels through the modification of lifestyle. However, very few data exist on the association between lockdown measures and vitamin D status in humans. For this...

Università della Svizzera italiana

SARS-CoV-2 Ig G among HealthcareWorkers and the General Population

Milani, Gregorio P. ; Bianchetti, Mario G. ; Togni, Giuseppe ; Schoenenberger, Andreas W. ; Muggli, Franco

In: Pathogens, 2021, vol. 10, no. 4, p. 6

It is assumed that healthcare workers are at the highest risk to be infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, few data from healthcare workers who do not primarily take care of patients with SARS-CoV-2 infection support this assumption. We investigated the prevalence of immunoglobulin G (Ig G) against SARS-CoV-2 among healthcare workers who do not...

Università della Svizzera italiana

Electrolyte and acid-base disorders triggered by aminoglycoside or colistin therapy : a systematic review

Scoglio, Martin ; Bronz, Gabriel ; Rinoldi, Pietro O. ; Faré, Pietro B. ; Betti, Céline ; Bianchetti, Mario G. ; Simonetti, Giacomo D. ; Gennaro, Viola ; Renzi, Samuele ; Lava, Sebastiano A. G. ; Milani, Gregorio P.

In: Antibiotics, 2021, vol. 10, no. 2, p. 9

Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated. We conducted a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses recommendations. Databases searched included United States National Library of...

Università della Svizzera italiana

Dietary chloride deficiency syndrome : pathophysiology, history, and systematic literature review

Signorelli, Giulia C. ; Bianchetti, Mario G. ; Jermini, Luca M. M. ; Agostoni, Carlo ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Lava, Sebastiano A. G.

In: Nutrients, 2020, vol. 12, no. 11, p. 10 p

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor salt intake and the mentioned electrolyte and acid–base abnormality. In patients with excessive loss of salt in the sweat or poor salt intake, the...

Università della Svizzera italiana

Atypical bacterial pathogens and small-vessel leukocytoclastic vasculitis of the skin in children : systematic literature review

Betti, Céline ; Camozzi, Pietro ; Gennaro, Viola ; Bianchetti, Mario G. ; Scoglio, Martin ; Simonetti, Giacomo D. ; Milani, Gregorio P. ; Lava, Sebastiano A. G. ; Ferrarini, Alessandra

In: Pathogens, 2021, vol. 10, no. 1, p. 9 p

Leukocytoclastic small-vessel vasculitis of the skin (with or without systemic involvement) is often preceded by infections such as common cold, tonsillopharyngitis, or otitis media. Our purpose was to document pediatric (≤18 years) cases preceded by a symptomatic disease caused by an atypical bacterial pathogen. We performed a literature search following the Preferred Reporting of...

Università della Svizzera italiana

Vitamin D status among male late adolescents living in southern Switzerland : role of body composition and lifestyle

Rabufetti, Andrea ; Milani, Gregorio P. ; Lava, Sebastiano A. G. ; Edefonti, Valeria ; Bianchetti, Mario G. ; Stettbacher, Andreas ; Muggli, Franco ; Simonetti, Giacomo

In: Nutrients, 2019, vol. 11, no. 11, p. 2727

Background: Poor vitamin D status is a worldwide health problem. Yet, knowledge about vitamin D status among adolescents in Southern Europe is limited. This study investigated concentrations and modulating factors of vitamin D in a healthy population of male late adolescents living in Southern Switzerland. Methods: All apparently healthy subjects attending for the medical evaluation before the...

Università della Svizzera italiana

Maintenance fluid therapy with saline, dextrose-supplemented saline or lactated Ringer in childhood: short-term metabolic effects

Ricciuti, Alessandra ; Milani, Gregorio P. ; Tarantino, Silvia ; Ghilardi, Roberta ; Lava, Sebastiano A.G. ; Alberzoni, Marco ; Bianchetti, Mario G. ; Agostoni, Carlo

In: Nutrients, 2020, vol. 12, no. 5, p. 8 p

Maintenance with isotonic fluids is recommended in children with gastroenteritis and failure of oral rehydration therapy. However, little is known on the short-term effects of the commonly prescribed intravenous solutions on metabolic balance in children. The aim of this study is to report on our experience with normal saline, dextrose-supplemented saline and lactated Ringer solution. Methods:...

Università della Svizzera italiana

Selective ß2-adrenoceptor agonists and relevant hyperlactatemia : systematic review and meta-analysis

Liedtke, Alina G. ; Lava, Sebastiano A. G. ; Milani, Gregorio P. ; Agostoni, Carlo ; Gilardi, Viola ; Bianchetti, Mario G. ; Treglia, Giorgio ; Faré, Pietro B.

In: Journal of clinical medicine, 2020, vol. 9, no. 1, p. 71

Selective ß2-agonists have been imputed as potential cause of l-hyperlactatemia since the 1970s. To document the prevalence of hyperlactatemia associated with selective ß2-agonists and to investigate the predisposing factors, we searched for published articles until April 2019 pertaining to the interplay of administration of selective ß2-agonists and circulating l-lactic acid in the Excerpta...