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Université de Fribourg

A multidimensional approach to impulsivity changes in mild Alzheimer’s disease and control participants: cognitive correlates

Rochat, Lucien ; Billieux, Joël ; Juillerat Van der Linden, Anne-Claude ; Annoni, Jean-Marie ; Zekry, Dina ; Gold, Gabriel ; Linden, Martial Van der

In: Cortex, 2013, vol. 49, no. 1, p. 90–100

Introduction: Impulsive behaviors are frequently described in brain-damaged patients, including patients with Alzheimer’s disease (AD). However, few studies have examined impulsivity changes and associated cognitive impairments in AD and healthy controls. Consequently, the first aim of this study was to compare patients with mild AD and matched controls on four dimensions of impulsivity...

Université de Fribourg

Weed or wheel! FMRI, behavioural, and toxicological investigations of how cannabis smoking affects skills necessary for driving

Battistella, Giovanni ; Fornari, Eleonora ; Thomas, Aurélien ; Mall, Jean-Frédéric ; Chtioui, Haithem ; Appenzeller, Monique ; Annoni, Jean-Marie ; Favrat, Bernard ; Maeder, Philippe ; Giroud, Christian

In: PLoS ONE, 2013, vol. 8, no. 1, p. e52545

Marijuana is the most widely used illicit drug, however its effects on cognitive functions underling safe driving remain mostly unexplored. Our goal was to evaluate the impact of cannabis on the driving ability of occasional smokers, by investigating changes in the brain network involved in a tracking task. The subject characteristics, the percentage of Δ9-Tetrahydrocannabinol in the joint, and...

Université de Fribourg

Feasibility and initial efficacy of a cognitive-behavioural group programme for managing anger and aggressiveness after traumatic brain injury

Aboulafia-Brakha, T. ; Buschbeck, C. Greber ; Rochat, L. ; Annoni, Jean-Marie

In: Neuropsychological Rehabilitation: An International Journal, 2013, vol. 23, no. 2, p. 216-233

This study assesses the feasibility of a cognitive-behavioural group programme for treating anger and aggressiveness after a traumatic brain injury (TBI). Five feasibility criteria were considered: demand, implementation, practicality, acceptability and initial efficacy. A self-report questionnaire of aggressiveness (AQ-12) was administered before the intervention (T1), one week following the...

Université de Fribourg

Poststroke fatigue following minor infarcts

Radman, Narges ; Staub, Fabienne ; Aboulafia-Brakha, Tatiana ; Berney, Alexandre ; Bogousslavsky, Julien ; Annoni, Jean-Marie

In: Neurology, 2012, p. -

Objective: To explore the potential relationship between fatigue following strokes and poststroke mood, cognitive dysfunction, disability, and infarct site and to determine the predictive factors in the development of poststroke fatigue (PSF) following minor infarcts.Methods: Ninety-nine functionally active patients aged less than 70 years with a first, nondisabling stroke (NIH Stroke Scale score...

Université de Fribourg

Neurocognitive aspects of translation

Annoni, Jean-Marie ; Lee-Jahnke, Hannelore ; Sturm, Annegret

In: Meta, 2012, vol. 57, no. 1, p. 96-107

Translation is at the centre of many cognitive domains such as pedagogy, linguistic, pragmatic, neurosciences, and social cognition. This multi-domain aspect is reflected in the current models of translation. Recently, cognitive neurosciences have unraveled some brain mechanisms in the bilingualism domain, and it is quite logical to transfer such knowledge to the field of translation as well as...

Université de Fribourg

Multiple sclerosis decreases explicit counterfactual processing and risk taking in decision making

Simioni, Samanta ; Schluep, Myriam ; Bault, Nadège ; Coricelli, Giorgio ; Kleeberg, Joerg ; Pasquier, Renaud A. Du ; Gschwind, Markus ; Vuilleumier, Patrik ; Annoni, Jean-Marie

In: PLoS ONE, 2012, vol. 7, no. 12, p. e50718

Deficits in decision making (DM) are commonly associated with prefrontal cortical damage, but may occur with multiple sclerosis (MS). There are no data concerning the impact of MS on tasks evaluating DM under explicit risk, where different emotional and cognitive components can be distinguished.Methods: We assessed 72 relapsing-remitting MS (RRMS) patients with mild to moderate disease and 38...

Université de Fribourg

inter- and intrahemispheric dissociations in ideomotor apraxia : a large-Scale lesion–symptom mapping study in subacute brain-damaged patients

Manuel, Aurelie L. ; Radman, Narges ; Mesot, Delphine ; Chouiter, Leila ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Cerebral Cortex, 2012, vol. 23, no. 12, p. 2781-2789

Pantomimes of object use require accurate representations of movements and a selection of the most task-relevant gestures. Prominent models of praxis, corroborated by functional neuroimaging studies, predict a critical role for left parietal cortices in pantomime and advance that these areas store representations of tool use. In contrast, lesion data points to the involvement of left inferior...

Université de Fribourg

Cognitive control of language production in bilinguals involves a partly independent process within the domain-general cognitive control network: Evidence from task-switching and electrical brain activity

Magezi, David A. ; Khateb, Asaid ; Mouthon, Michael ; Spierer, Lucas ; Annoni, Jean-Marie

In: Brain and Language, 2012, vol. 122, no. 1, p. 55–63

In highly proficient, early bilinguals, behavioural studies of the cost of switching language or task suggest qualitative differences between language control and domain-general cognitive control. By contrast, several neuroimaging studies have shown an overlap of the brain areas involved in language control and domain-general cognitive control. The current study measured both behavioural...

Université de Fribourg

Mutism and amnesia following high-Voltage electrical injury: psychogenic symptomatology triggered by organic dysfunction?

Mishra, Nishant K. ; Russmann, Heike ; Granziera, Cristina ; Maeder, Philippe ; Annoni, Jean-Marie

In: European Neurology, 2011, vol. 66, no. 4, p. 229-234

Background: Mutism and dense retrograde amnesia are found both in organic and dissociative contexts. Moreover, dissociative symptoms may be modulated by right prefrontal activity. A single case, M.R., developed left hemiparesis, mutism and retrograde amnesia after a high-voltage electric shock without evidence of lasting brain lesions. M.R. suddenly recovered from his mutism following a mild...

Université de Fribourg

Language and syntactic impairment following stroke in late bilingual aphasics

Tschirren, Muriel ; Laganaro, Marina ; Michel, Patrik ; Martory, Marie-Dominique ; Di Pietro, Marie ; Abutalebi, Jubin ; Annoni, Jean-Marie

In: Brain and Language, 2011, vol. 119, no. 3, p. 238-242

Purpose :Bilingual aphasia generally affects both languages. However, the age of acquisition of the second language (L2) seems to play a role in the anatomo-functional correlation of the syntactical/grammatical processes, thus potentially influencing the L2 syntactic impairment following a stroke. The present study aims to analyze the influence of late age of acquisition of the L2 on syntactic...