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Consortium of Swiss Academic Libraries

Obesity and aging: determinants of endothelial cell dysfunction and atherosclerosis

Barton, Matthias

In: Pflügers Archiv - European Journal of Physiology, 2010, vol. 460, no. 5, p. 825-837

Université de Fribourg

Opposing and uncoupling effects of mTOR and S6K1 in the regulation of endothelial tissue factor expression

Ming, Xiu-Fen ; Rajapakse, Angana Gupta ; Carvas, João Miguel ; Ruffieux, Jean ; Yang, Zhihong

In: Febs Letters, 2010, vol. 58, no. 1, p. 135-140

Rapamycin has been reported to enhance tissue factor (TF) expression. The present study investigated roles of mammalian target of rapamycin (mTOR) and its downstream S6K1 in this process. We showed here that, consistent with rapamycin, knocking-down mTOR enhanced thrombin-induced TF mRNA and protein levels, whereas silencing S6K1 mitigated up-regulation of TF protein but not TF mRNA level. The...

Consortium of Swiss Academic Libraries

Polarized Actin Structural Dynamics in Response to Cyclic Uniaxial Stretch

Huang, Lawrence ; Helmke, Brian

In: Cellular and Molecular Bioengineering, 2015, vol. 8, no. 1, p. 160-177

Consortium of Swiss Academic Libraries

A Semi-Automatic Method for Image Analysis of Edge Dynamics in Living Cells

Huang, Lawrence ; Helmke, Brian

In: Cellular and Molecular Bioengineering, 2011, vol. 4, no. 2, p. 205-219