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Université de Lausanne

Contribution to the Development of the LHCb Vertex Locator Readout Electronics

Ermoline, Iouri ; Bay, Aurélio (Dir.)

Thèse de doctorat : Université de Lausanne : 2003.

The LHCb experiment is being built at the future LHC accelerator at CERN. It is a forward single-arm spectrometer dedicated to precision measurements of CP violation and rare decays in the b quark sector. Presently it is finishing its R

Université de Lausanne

Cryo-negative staining: advantages and applications for three-dimensional electron microscopy of biological macromolecules

De Carlo, Sacha ; Dubochet, Jacques (Dir.)

Thèse de doctorat : Université de Lausanne : 2002.

Many biological specimens do not arrange themselves in ordered assemblies (tubular or flat 2D crystals) suitable for electron crystallography, nor in perfectly ordered 3D crystals for X-ray diffraction; many other are simply too large to be approached by NMR spectroscopy. Therefore, single-particles analysis has become a progressively more important technique for structural determination of large...

Université de Lausanne

Phytochemical investigation of plants used in African traditional medicine: "Dioscorea sylvatica" (Dioscoreaceae), "Urginea altissima" (Liliaceae), "Jamesbrittenia fodina" and "Jamesbrittenia elegantissima" (Scrophulariaceae)

Cogne, Anne-Laure ; Hostettmann, Kurt (Dir.)

Thèse de doctorat : Université de Lausanne : 2002.

In certain African countries, medicinal plants represent the unique source of to 90% of the population. The knowledge of traditional healers represents a basis for the pharmacological and phytochemical investigation of these natural medicines. This work first focused on the validation of use of two plants frequently employed in traditional medicine, Dioscorea sylvatica (Dioscoreaceae) and Urginea...

Université de Lausanne

Integral cohomology of finite postnikov towers

Clément, Alain ; Arlettaz, Dominique (Dir.)

Thèse de doctorat : Université de Lausanne : 2002.

By the work of H. Cartan, it is well known that one can find elements of arbitrarilly high torsion in the integral (co)homology groups of an Eilenberg-MacLane space K(G,n), where G is a non-trivial abelian group and n>1. The main goal of this work is to extend this result to H-spaces having more than one non-trivial homotopy groups. In order to have an accurate hold on H. Cartan's result, we...

Université de Lausanne

Impact des maladies rhumatismales sur la population âgée en Suisse et sa consommation de soins

Mariller, Marjorie ; Santos-Eggimann, B. (Dir.)

Thèse de doctorat : Université de Lausanne : 2002.

Rheumatic diseases are frequently observed in elderly people and have an important impact on tlieir life qurlity. There are fe1.v Swiss stuciies on the epiciemio!ogica! situttien and on the impact of such diseases on the use of health services. This thesis aims at studying the current knowledge based on Swiss and international literature and at establishing the situation in Switzerland from a...

Université de Lausanne

Chirurgie de réduction de volume pulmonaire: Suivi des 26 premiers patients à Lausanne

Dominicé Dao, Melissa ; Fitting, Jean-William (Dir.)

Thèse de doctorat : Université de Lausanne : 2001.

Ce travail concerne les 26 premiers patients opérés à Lausanne de juillet 1995 à avril 1998 d’une gie de réduction de volume pulmonaire pour un emphysème sévère. Il présente leurs actéristiques préopératoires générales, leur évaluation radiologique et cardiologique, ainsi que mesures fonctionnelles pulmonaires. Il examine ensuite la technique opératoire, la période...

Université de Lausanne

Geology, correlations, and geodynamic evolution of the Biga Peninsula (NW Turkey)

Beccaletto, Laurent ; Stampfli, Gérard M. (Dir.)

Thèse de doctorat : Université de Lausanne : 2003.

The purpose of this study is to unravel the geodynamic evolution of the Biga Peninsula (NW Turkey) through the detailed study of two poorly known areas, the Çetmi mélange and the Ezine zone (i.e. the Ezine Group and the Denizgören ophiolite). The methodology was based on a detailed field work and a multidisciplinary approach. • The accretion-related Çetmi mélange is mainly cropping out...

Université de Lausanne

Characterization and functional identification of a novel plant extradiol 4,5-dioxygenase involved in betalain pigment biosynthesis in portulaca grandiflora

Christinet, Laurent ; Zrÿd, Jean-Pierre (Dir.)

Thèse de doctorat : Université de Lausanne : 2004.

Betalains are violet and yellow chromo-alkaloid pigments present in plants belonging to the order Caryophyllales and also in the fungal genera Amanita and Hygrocybe. Their short biosynthetic pathway is chemically well understood since many years, but enzymes involved in the plant pathway are still uncharacterized. The DOPA-dioxygenase from Amanita muscaria was identified (Girod and Zrÿd, 1991a),...