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Université de Fribourg

Acute alcohol intoxication and expectations reshape the spatiotemporal functional architecture of executive control

Ribordy Lambert, Farfalla ; Wicht, Corentin A. ; Mouthon, Michael ; Spierer, Lucas

In: NeuroImage, 2020, vol. 215, p. 116811

While the deleterious effects of acute ethyl alcohol intoxication on executive control are well-established, the underlying spatiotemporal brain mechanisms remain largely unresolved. In addition, since the effects of alcohol are noticeable to participants, isolating the effects of the substance from those related to expectations represents a major challenge. We addressed these issues using a...

Université de Fribourg

Effects of continuous theta burst stimulation over the left DLPFC on mother tongue and second language production in late bilinguals: a behavioral and ERP study

Jost, Lea B. ; Pestalozzi, Maria I. ; Cazzoli, Dario ; Mouthon, Michael ; Müri, René M. ; Annoni, Jean‑Marie

In: Brain Topography, 2020, vol. 33, no. 4, p. 504–518

Clinical, neuroimaging, and non-invasive brain stimulation studies have associated the dorsolateral prefrontal cortex (DLPFC) with the multilingual language control system. Here, we investigated if this role is increased during the processing of the non- dominant language due to the higher cognitive/attentional demands. We used an inhibitory repetitive transcranial magnetic stimulation (rTMS)...

Université de Fribourg

Health concepts among socially disadvantaged children in France, Germany and Switzerland

Grimminger-Seidensticker, Elke ; Aceti, Monica ; Knobé, Sandrine ; Vieille Marchiset, Gilles

In: Health Promotion International, 2020, vol. 35, no. 1, p. 17–26

As health concepts develop through exposure to, and experience with particular contexts, and as health concepts influence health behaviour, it is important for actors in health promotion programmes to understand an individual’s health concepts. This study focussed on health concepts among socially disadvantaged children in France, Germany, Italy and Switzerland—a hitherto less researched...

Université de Fribourg

Coronavirus infections in children including covid-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children

Petra, Zimmermann ; Nigel, Curtis

In: The Pediatric Infectious Disease Journal, 2020, vol. 39, no. 5, p. 355–368

Coronaviruses (CoVs) are a large family of enveloped, single-stranded, zoonotic RNA viruses. Four CoVs commonly circulate among humans: HCoV2-229E, -HKU1, -NL63 and -OC43. However, CoVs can rapidly mutate and recombine leading to novel CoVs that can spread from animals to humans. The novel CoVs severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and Middle East...

Université de Fribourg

Granzyme B attenuates bacterial virulence by targeting secreted factors

López León, Diego ; Matthey, Patricia ; Fellay, Isabelle ; Blanchard, Marianne ; Martinvalet, Denis ; Mantel, Pierre-Yves ; Filgueira, Luis ; Walch, Michael

In: iScience, 2020, vol. 23, no. 3, p. 100932

Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show that granzyme B degrades multiple secreted virulence mediators from Listeria monocytogenes,...

Université de Fribourg

Osteopathy in the French-speaking part of Switzerland: Practitioners’ profile and scope of back pain management

Bill, Anne-Sylvie ; Dubois, Julie ; Pasquier, Jérôme ; Burnand, Bernard ; Rodondi, Pierre-Yves

In: PLOS ONE, 2020, vol. 15, no. 5, p. e0232607

Background: Osteopathy is commonly used for spinal pain, but knowledge about back pain management by osteopaths is scarce.Objective: The aim of this study was to survey osteopaths across the French-speaking part of Switzerland about the scope of their practice and their management of patients with back pain.Design: This cross- sectional observational study was based on an online survey...

Université de Fribourg

Palynological study of carbonated mounds during the holocene along the atlantic and mediterranean moroccan margins

Rachid, Jihad ; Hssaida, Touria ; Hamoumi, Naima ; Terhzaz, Loubna ; Spezzaferri, Silvia ; Frank, Norbert ; Daghor, Lamia

In: Review of Palaeobotany and Palynology, 2020, vol. 278, p. 104213

A palynological study of carbonate mounds of Atlantic and Mediterranean Moroccan margins was conducted on sediment boxcores MD13-3441, MD13-3456, MD13-3461, MD13-3465, MD13-3468 collected during the oceanographic cruise MD 194/Eurofleet - GATEWAY, which took place on June 2013.The organic remaining revealed a dominance of dinoflagellate cysts over the continental fraction, which showed very...

Université de Fribourg

Emerging climate signals in the Lena River catchment: a non-parametric statistical approach

Pohl, Eric ; Grenier, Christophe ; Vrac, Mathieu ; Kageyama, Masa

In: Hydrology and Earth System Sciences, 2020, vol. 24, no. 5, p. 2817–2839

Climate change has far-reaching implications in permafrost-underlain landscapes with respect to hydrology, ecosystems, and the population's traditional livelihoods. In the Lena River catchment, eastern Siberia, changing climatic conditions and the associated impacts are already observed or expected. However, as climate change progresses the question remains as to how far we are along this...

Université de Fribourg

Synoptic conditions and atmospheric moisture pathways associated with virga and precipitation over coastal Adélie Land in Antarctica

Jullien, Nicolas ; Vignon, Étienne ; Sprenger, Michael ; Aemisegger, Franziska ; Berne, Alexis

In: The Cryosphere, 2020, vol. 14, no. 5, p. 1685–1702

Precipitation falling over the coastal regions of Antarctica often experiences low-level sublimation within the dry katabatic layer. The amount of water that reaches the ground surface is thereby considerably reduced. This paper investigates the synoptic conditions and the atmospheric transport pathways of moisture that lead to either virga – when precipitation is completely sublimated –...

Université de Fribourg

A taxonomic revision of geoemydid turtles from Siwalik-age of India and Pakistan

Garbin, Rafaella C. ; Bandyopadhyay, Saswati ; Joyce, Walter G.

In: European Journal of Taxonomy, 2020, no. 652, p. -

Neogene (Siwalik-aged) deposits from India and Pakistan have yielded many vertebrate fossils, of which most were named during the 19th century, including numerous geoemydid turtles. In contrast to many other faunal components from the Siwaliks, geoemydids have not undergone taxonomic revision for more than a century and most fossils have therefore been believed to correspond to recent taxa....