Thèse de doctorat : Université de Fribourg, 2006 ; no 1541.
Trypanosoma brucei is one of the earliest diverging eukaryotes with a bona fide mitochondrion. In contrast to most other eukaryotes, it has a single mitochondrion only which shows a large network-like morphology. This unique feature makes T. brucei an excellent model to study some unique aspects of mitochondrial biology. In the first part of this thesis, we used T. brucei as a model to study the...
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Thèse de doctorat : Université de Fribourg, 2006 ; no 1544.
The protozoon parasite Trypanosoma brucei is the causing agent of human sleeping sickness. Besides its clinical importance T. brucei is also an excellent model for basic research since it has many unique features. The mitochondrion of T. brucei, for example, lacks tRNA genes. The tRNAs required for mitochondrial translation are therefore encoded in the nucleus and imported from the cytosol [1]....
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Thèse de doctorat : Université de Fribourg, 2002 ; no 1372.
The goal of my Ph.D. thesis was to study the larval chemosensory system of the fruit fly Drosophila melanogaster, both in terms of its organization and neurotransmitter content. My studies were based on the enhancer trap technique, which provides useful neuronal marker lines and allows ectopic expression of any transgene of interest in the labeled cells. Four enhancer trap lines selected for...
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