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Université de Fribourg

A consensus estimate for the ice thickness distribution of all glaciers on Earth

Farinotti, Daniel ; Huss, Matthias ; Fürst, Johannes J. ; Landmann, Johannes ; Machguth, Horst ; Maussion, Fabien ; Pandit, Ankur

In: Nature Geoscience, 2019, vol. 12, no. 3, p. 168–173

Knowledge of the ice thickness distribution of the world’s glaciers is a fundamental prerequisite for a range of studies. Projections of future glacier change, estimates of the available freshwater resources or assessments of potential sea-level rise all need glacier ice thickness to be accurately constrained. Previous estimates of global glacier volumes are mostly based on scaling...

Université de Fribourg

Analysis of temporal and spatial variations in hydrometeorological elements in the Yarkant River Basin, China

Wei, Ren-juan ; Peng, Liang ; Liang, Chuan ; Haemmig, Christoph ; Huss, Matthias ; Mu, Zhen-xia ; He, Ying

In: Journal of Water and Climate Change, 2019, vol. 10, no. 1, p. 167–180

Yarkant River is a tributary of Tarim River in China, and the basin lacks observational data. To investigate past climatic variations and predict future climate changes, precipitation, air temperature and runoff data from Kaqun hydrological station are analysed at monthly and seasonal scales using detrended fluctuation analysis (DFA). Results show that DFA scaling exponents of monthly...

Université de Fribourg

Pleistocene sea-floor fibrous crusts and spherulites in the Danakil Depression (Afar, Ethiopia)

Jaramillo‐Vogel, David ; Foubert, Anneleen ; Braga, Juan Carlos ; Schaegis, Jean‐Charles ; Atnafu, Balemwal ; Grobéty, Bernard ; Kidane, Tesfaye

In: Sedimentology, 2019, vol. 66, no. 2, p. 480–512

Pleistocene fibrous aragonite fabrics, including crusts and spherules, occur in the Danakil Depression (Afar, Ethiopia) following the deposition of two distinctive Middle and Late Pleistocene coralgal reef units and pre‐dating the precipitation of evaporites. Crusts on top of the oldest reef unit (Marine Isotope Stage 7) cover and fill cavities within a red algal framework. The younger...

Université de Fribourg

To split or not to split Anthracotherium? A phylogeny of Anthracotheriinae (Cetartiodactyla: Hippopotamoidea) and its palaeobiogeographical implications

Scherler, Laureline ; Lihoreau, Fabrice ; Becker, Damien

In: Zoological Journal of the Linnean Society, 2019, vol. 185, no. 2, p. 487–510

Since its first erection almost 200 years ago, palaeontologists have assigned to the genus Anthracotherium many species, some with dubious descriptions. Although it is a key taxon for specifying the invasion of Europe by terrestrial mammals during the well-studied Grande Coupure Event at the beginning of the Oligocene, the genus has never been reviewed before. A recent interest in the...

Université de Fribourg

Constraining hydrological model parameters using water isotopic compositions in a glacierized basin, Central Asia

He, Zhihua ; Unger-Shayesteh, Katy ; Vorogushyn, Sergiy ; Weise, Stephan M. ; Kalashnikov, Olga ; Gafurov, Abror ; Duethmann, Doris ; Barandun, Martina ; Merza, Bruno

In: Journal of Hydrology, 2019, vol. 571, p. 332–348

Water stable isotope signatures can provide valuable insights into the catchment internal runoff processes. However, the ability of the water isotope data to constrain the internal apportionments of runoff components in hydrological models for glacierized basins is not well understood. This study developed an approach to simultaneously model the water stable isotopic compositions and runoff...

Université de Fribourg

European practical and patient-centred guidelines for adult obesity management in primary care

Durrer Schutz, D. ; Busetto, L. ; Dicker, D. ; Farpour-Lambert, N. ; Pryke, R. ; Toplak, H. ; Widmer, D. ; Yumuk, V. ; Schutz, Yves

In: Obesity Facts, 2019, vol. 12, no. 1, p. 40–66

The first contact for patients with obesity for any medical treatment or other issues is generally with General Practitioners (GPs). Therefore, given the complexity of the disease, continuing GPs’ education on obesity management is essential. This article aims to provide obesity management guidelines specifically tailored to GPs, favouring a practical patient-centred approach. The focus is...

Université de Fribourg

Comparison of conventional and individualized 1-MET values for expressing maximum aerobic metabolic rate and habitual activity related energy expenditure

Heydenreich, Juliane ; Schutz, Yves ; Melzer, Katarina ; Kayser, Bengt

In: Nutrients, 2019, vol. 11, no. 2, p. 458

The maximum aerobic metabolic rate can be expressed in multiple metabolically equivalent tasks (MET), i.e., METmax. The purpose was to quantify the error when the conventional (3.5 mL∙kg−1∙min−1) compared to an individualized 1-MET-value is used for calculating METmax and estimating activity energy expenditure (AEE) in endurance-trained athletes (END) and active healthy controls...

Université de Fribourg

Excitonic channels from bio-inspired templated supramolecular assembly of J-aggregate nanowires

Anantharaman, Surendra B. ; Messmer, Daniel ; Sadeghpour, Amin ; Salentinig, Stefan ; Nüescha, Frank ; Heier, Jakob

In: Nanoscale, 2019, vol. 11, no. 14, p. 6929–6938

Supramolecular assemblies with controlled morphology are of paramount importance for energy transport in organic semiconductors. Despite considerable freedom in molecular design, the preparation of dyes that form one dimensional J-aggregates is challenging. Here, we demonstrate a simple and effective route to functionalize dendronized polymers (DPs) with J-aggregates to construct tubular...

Université de Fribourg

Magneto-responsive cell culture substrates that can be modulated in situ

Crippa, Federica ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 51–54

Understanding the interaction between cells and their environment is fundamental for mechanobiology. To mimic the behavior of cells in physiological and pathological conditions, synthetic substrates must have topographical and/or mechanical properties that evolve in time. Dynamic substrates mainly rely on stimuli-responsive materials where an external stimulus induces controlled variations in...

Université de Fribourg

A bio-inspired amplification cascade for the detection of rare cancer cells

Rüegg, Curzio ; Reis, Corine ; Rafiee, Sarah ; Rodriguez-Lorenzoa, Laura ; List, Jonathan ; Rothen-Rutishauser, Barbara ; Mayer, Michael ; Petri-Fink, Alke

In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 63–68

The main cause of cancer-related death is due to cancer cell spreading and formation of secondary tumors in distant organs, the so-called metastases. Metastatic cancer cells are detectable in the blood of cancer patients as circulating tumor cells (CTC) and may be exploited for prognostic and monitoring purposes, including in breast cancer. Due to their very low frequency, however, their...