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Université de Fribourg

Towards deciphering variations of heart regeneration in fish

Jaźwińska, Anna ; Blanchoud, Simon

In: Current Opinion in Physiology, 2020, vol. 14, p. 21–26

Among adult vertebrates, the zebrafish presents the rather exceptional capacity to efficiently regenerate its heart after injury. This bony fish has thus become a leading genetic model organism to elucidate the natural mechanisms of successful cardiac restoration. Given its potential biomedical significance, parallel analyses between zebrafish and mammals are aiming at the identification of...

Université de Fribourg

Richness, phylogenetic diversity, and abundance all have positive effects on invader performance in an arid ecosystem

El‐Barougy, Reham ; Mac, Ivor, J. Scott ; Arnillas, Carlos A. ; Nada, Reham M. ; Khedr, Abdel‐Hamid A. ; Cadotte, Marc W.

In: Ecosphere, 2020, vol. 11, no. 2, p. -

In search of generalities in biological invasions, it is sometimes forgotten that invader success can be a function of both the diversity of the invaded community and the relatedness of the invader relative to community residents. Both qualities are likely to be especially important in stressful ecosystems, and identifying the species and community attributes that influence biological ...

Université de Fribourg

The Pseudomonas aeruginosa lectin LecB causes integrin internalization and inhibits epithelial wound healing

Thuenauer, Roland ; Landi, Alessia ; Trefzer, Anne ; Altmann, Silke ; Wehrum, Sarah ; Eierhoff, Thorsten ; Diedrich, Britta ; Dengjel, Jörn ; Nyström, Alexander ; Imberty, Anne ; Römer, Winfried

In: mBio, 2020, vol. 11, no. 2, p. -

The opportunistic bacterium Pseudomonas aeruginosa produces the fucose- specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly binds to the glycosylated moieties of β1-integrins on the basolateral plasma membrane of epithelial...

Université de Fribourg

The last surviving Thalassochelydia — A new turtle cranium from the Early Cretaceous of the Purbeck Group (Dorset, UK)

Anquetin, Jérémy ; André, Charlotte

In: PaleorXiv

Background. The mostly Berriasian (Early Cretaceous) Purbeck Group of southern England has produced a rich turtle fauna dominated by the freshwater paracryptodires Pleurosternon bullockii and Dorsetochelys typocardium. Each of these species is known by numerous relatively complete shells and by a single cranium. The two other turtles found in the Purbeck Group (Hylaeochelys belli, a species of...

Haute Ecole pédagogique Fribourg

Die Philo-Kinder. : Ein Lehrmittel für Kindergarten und Unterstufe (Zyklus 1)

Bleisch, Petra ; Bietenhard, Sophia

In: erg.ch – Materialien zum Fach Ethik, Religionen, Gemeinschaft, 2020, p. 1-10

Kinder zwischen vier und acht Jahren sind wissbegierig und stellen viele Fragen. Dazu gehören auch die grossen «Warum-Fragen», die nach Lebenssinn und dem guten und rechten Handeln fragen, also ethische und existentielle Dimensionen enthalten. Bislang fehlte aber ein Lehrmittel für die Eingangsstufe, welches solche Fragen der Kinder aufnimmt, um sie gezielt in der Schule bearbeiten zu...

Haute Ecole pédagogique Fribourg

Une feuille de route numérique pour évaluer formativement la progression des étudiant.e.s en contexte d’enseignement à distance.

Coen, Pierre-François ; Pellegrini, Sheila

In: Évaluer. Journal international de recherche en éducation et formation, 2020, p. 59-65

Dans le contexte de la formation des enseignant.e.s de la Haute école pédagogiques de Fribourg, l’usage d’une feuille de route numérique destinée à favoriser l’évaluation formative à distance a été utilisée dans le cadre d’un séminaire pratique de méthodologie de la recherche. Cette feuille de route se présente sous la forme d’un document Google partagé entre les...

Université de Fribourg

Students' Problem Behaviors as Sources of Teacher Stress in Special Needs Schools for Individuals With Intellectual Disabilities

Amstad, Meta ; Müller, Christoph M.

In: Frontiers in Education, 2020, vol. 4, p. 1-11

Students with intellectual disabilities in special needs schools often exhibit high levels of problem behaviors. Besides of the challenges for the concerned individuals, peers, and their caregivers, problem behaviors can also be a source of stress for teachers. However, less is known on which exact behaviors are perceived as how stressful in special needs schools for students with intellectual...

Université de Fribourg

Computational network biology: Data, models, and applications

Liu, Chuang ; Ma, Yifang ; Zhao, Jing ; Nussinov, Ruth ; Zhang, Yi-Cheng ; Cheng, Feixiong ; Zhang, Zi-Ke

In: Physics Reports, 2020, vol. 846, p. 1–66

Biological entities are involved in intricate and complex interactions, in which uncovering the biological information from the network concepts are of great significance. Benefiting from the advances of network science and high-throughput biomedical technologies, studying the biological systems from network biology has attracted much attention in recent years, and networks have long been...