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Université de Fribourg

Measuring physical load in soccer: strengths and limitations of 3 different methods

Fischer-Sonderegger, Karin ; Taube, Wolfgang ; Rumo, Martin ; Tschopp, Markus

In: International Journal of Sports Physiology and Performance, 2019, vol. 14, no. 5, p. 627–634

To investigate the strengths and limitations of different indicators to measure physical load. Furthermore, indicators were evaluated for discrimination between performance levels and playing positions. Methods: Ninety positional match files from 70 elite players and 91 match files from 69 subelite players were collected during 14 official under-18 matches using a local position measurement...

Université de Fribourg

Mental imagery and colour cues can prevent interference between motor tasks

Lauber, Benedikt ; Kurz, Alexander ; Gollhofer, Albert ; Taube, Wolfgang

In: Neuropsychologia, 2019, vol. 124, p. 202–207

Motor interference can be observed when two motor tasks are learnt in subsequent order. The aim of the current study was to test two approaches potentially mitigating interference effects. The first approach used contextual colour cues requiring only little cognitive attention thus being assumed to be primarily implicit while the second, mental practice/rehearsal that demands much more active...

Université de Fribourg

The faster, the better? Relationships between run-up speed, the degree of difficulty (D-score), height and length of flight on vault in artistic gymnastics

Schärer, Christoph ; Lehmann, Thomas ; Naundorf, Falk ; Taube, Wolfgang ; Hübner, Klaus

In: PLOS ONE, 2019, vol. 14, no. 3, p. e0213310

On vault in artistic gymnastics, a high run-up speed is thought to be important when performing difficult vaults. To test this assumption in a large cohort of elite athletes, we calculated the correlations between the run-up speed, scores, height and length of flight for handspring-, Tsukahara- and Yurchenko-style vaults and compared the performances of male and female elite and junior...

Université de Fribourg

Does the bilingual advantage in cognitive control exist and if so, what are its modulating factors? A systematic review

Noort, Maurits van den ; Struys, Esli ; Bosch, Peggy ; Jaswetz, Lars ; Perriard, Benoît ; Yeo, Sujung ; Barisch, Pia ; Vermeire, Katrien ; Lee, Sook-Hyun ; Lim, Sabina

In: Behavioral Sciences, 2019, vol. 9, no. 3, p. 27

Recently, doubts were raised about the existence of the bilingual advantage in cognitive control. The aim of the present review was to investigate the bilingual advantage and its modulating factors. We searched the Medline, ScienceDirect, Scopus, and ERIC databases for all original data and reviewed studies on bilingualism and cognitive control, with a cut-off date of 31 October 2018, thereby...

Université de Fribourg

Erratic movement disorders disclosing Graves’ disease and paralleling thyroid function but not autoantibody levels

Delhasse, Sébastien ; Debove, Ines ; Arnold-Kunz, Gabriella ; Ghika, Joseph-André ; Chabwine, Joelle Nsimire

In: Journal of International Medical Research, 2019, vol. 47, no. 3, p. 1378–1386

Graves’ disease (GD) is an autoimmune pathology characterized by hyperthyroidism and the presence of specific anti-thyroid antibodies. Neurological symptoms such as seizures, cognitive impairment, and tremor can be observed during the course of GD, but more complex movement disorders such as chorea and myoclonus are less frequent. The mechanisms underlying movement disorders in GD are not...

Université de Fribourg

Embodied semantics in a second language: critical review and clinical implications

Monaco, Elisa ; Jost, Lea B. ; Gygax, Pascal M. ; Annoni, Jean-Marie

In: Frontiers in Human Neuroscience, 2019, vol. 13, p. -

The role of the sensorimotor system in second language (L2) semantic processing as well as its clinical implications for bilingual patients has hitherto been neglected. We offer an overview of the issues at stake in this under-investigated field, presenting the theoretical and clinical relevance of studying L2 embodiment and reviewing the few studies on this topic. We highlight that (a) the...

Université de Fribourg

Factors that influence the immune response to vaccination

Zimmermann, Petra ; Curtis, Nigel

In: Clinical Microbiology Reviews, 2019, vol. 32, no. 2, p. e00084-18

There is substantial variation between individuals in the immune response to vaccination. In this review, we provide an overview of the plethora of studies that have investigated factors that influence humoral and cellular vaccine responses in humans. These include intrinsic host factors (such as age, sex, genetics, and comorbidities), perinatal factors (such as gestational age, birth weight,...

Université de Fribourg

PARP inhibition induces Akt-mediated cytoprotective effects through the formation of a mitochondria-targeted phospho-ATM-NEMO-Akt-mTOR signalosome

Tapodi, Antal ; Bognar, Zita ; Szabo, Csaba ; Gallyas, Ferenc ; Sumegi, Balázs ; Hocsak, Enikő

In: Biochemical Pharmacology, 2019, vol. 162, p. 98–108

The cytoprotective effect of poly(ADP-ribose) polymerase 1 (PARP1) inhibition is well documented in various cell types subjected to oxidative stress. Previously, we have demonstrated that PARP1 inhibition activates Akt, and showed that this response plays a critical role in the maintenance of mitochondrial integrity and in cell survival. However, it has not yet been defined how nuclear PARP1...

Université de Fribourg

CX 3 CR1-CX 3 CL1-dependent cell-to-cell Japanese encephalitis virus transmission by human microglial cells

Lannes, Nils ; Garcia-Nicolàs, Obdullio ; Démoulins, Thomas ; Summerfield, Artur ; Filgueira, Luis

In: Scientific Reports, 2019, vol. 9, no. 1, p. 4833

The neurotropic Japanese encephalitis virus (JEV) is responsible for Japanese encephalitis, an uncontrolled inflammatory disease of the central nervous system. Microglia cells are the unique innate immune cell type populating the brain that cross- communicate with neurons via the CX3CR1-CX3CL1 axis. However, microglia may serve as a viral reservoir for JEV. Human microglia are able to transmit...

Université de Fribourg

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Petrini, Francesco M. ; Mazzoni, Alberto ; Rigosa, Jacopo ; Giambattistelli, Federica ; Granata, Giuseppe ; Barra, Beatrice ; Pampaloni, Alessandra ; Guglielmelli, Eugenio ; Zollo, Loredana ; Capogrosso, Marco ; Micera, Silvestro ; Raspopovic, Stanisa

In: BioMedical Engineering OnLine, 2019, vol. 18, no. 1, p. 44

The usability of dexterous hand prostheses is still hampered by the lack of natural and effective control strategies. A decoding strategy based on the processing of descending efferent neural signals recorded using peripheral neural interfaces could be a solution to such limitation. Unfortunately, this choice is still restrained by the reduced knowledge of the dynamics of human efferent...