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Université de Fribourg

Nine hole peg test and transcranial magnetic stimulation: useful to evaluate dexterity of the hand and disease progression in amyotrophic lateral sclerosis

Czell, David ; Neuwirth, Christoph ; Weber, Markus ; Sartoretti-Schefer, Sabine ; Gutzeit, Andreas ; Reischauer, Carolin

In: Neurology Research International, 2019, vol. 2019, p. 1–5

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with involvement of the upper and lower motor neurons. Since the loss of fine motor skills is one of the earliest signs of ALS, the hypothesis was tested if the nine hole PEG test (NHPT) and transcranial magnet stimulation (TMS) with resting-motor threshold (RMT) could be useful in monitoring disease progression. Methods. We...