Université de Neuchâtel

Rhodium-Catalysed Carbonylation of Methanol Using a New Multifunctional Ligand - Isolation and Structural Characterisation of the Macrocycle [Rh2I6(CO)2(C6H4N3CH2CO2C4H2SCO2CH2C6H4N3)]2

Thomas, Christophe M. ; Neels, Antonia ; Stoeckli-Evans, Helen ; Süss-Fink, Georg

In: European Journal of Inorganic Chemistry, 2001, vol. 12, p. 3005 - 3008

The new multifunctional ligand thiophene-2,5-bis(carboxylatomethylenebenzotriazole) (1) reacts with [RhCl(CO)2]2 to give the rhodium complex [RhCl(CO)(1)]2 (2), which was found to catalyse efficiently the iodide-mediated carbonylation of methanol. The macrocyclic carbonyliodorhodium complex...

Université de Neuchâtel

Dendritic Systems Based on Dinuclear Ruthenium or Rhodium Units Generating Peripheral Catalytic Sites

Chérioux, Frédéric ; Thomas, Christophe M. ; Therrien, Bruno ; Süss-Fink, Georg

In: Chemistry - A European Journal, 2002, vol. 8, p. 4377 - 4382

A series of dendritic cations 1-4 containing Ru2S3 or Rh2S3 units, either in the core or in the dendrons, has been synthesized and characterized. The X-ray crystal structure analysis of 2-Cl shows a trigonal bipyramidal Rh2S3 core with propeller-like para-hydroxyphenyl substituents at the sulfur atoms. Reaction...

Université de Neuchâtel

New Diphosphine Ligands Containing Ethyleneglycol and Amino Alcohol Spacers for the Rhodium-Catalyzed Carbonylation of Methanol

Thomas, Christophe M. ; Mafua, Roger ; Therrien, Bruno ; Rusanov, Eduard ; Stoeckli-Evans, Helen ; Süss-Fink, Georg

In: Chemistry - A European Journal, 2002, vol. 8, p. 3343 - 3352

The new diphosphine ligands Ph2PC6H4C(O)X(CH2)2OC(O)C6H4PPh2 (1: X=NH; 2: X=NPh; 3: X=O) and Ph2PC6H4C(O)O(CH2)2O(CH2)2OC(O)C6H4PPh2 (5) as well as the monophosphine ligand...

Université de Neuchâtel

Specific reactivity of SH versus OH functions towards dinuclear arene ruthenium units : synthesis of cationic complexes of the type [(arene)2Ru2(SR)3]+

Chérioux, Frédéric ; Thomas, Christophe M. ; Monnier, Tiffany ; Süss-Fink, Georg

In: Polyhedron, 2003, vol. 22, p. 543-548

The reaction of [(arene)RuCl2]2 (arene=C6H6, p-Me—C6H4—iPr, C6Me6) with p-thiocresol, 2-mercaptoethanol and p-mercaptophenol in refluxing ethanol gives the tris-thiolato complexes [(arene) 2Ru2(SR)3]+...

Université de Neuchâtel

Aqueous oxidation of alcohols catalyzed by artificial metalloenzymes based on the biotin–avidin technology

Thomas, Christophe M. ; Letondor, Christophe ; Humbert, Nicolas ; Ward, Thomas R.

In: Journal of Organometallic Chemistry, 2005, vol. 690, p. 4488-4491

Based on the incorporation of biotinylated organometallic catalyst precursors within (strept)avidin, we have developed artificial metalloenzymes for the oxidation of secondary alcohols using tert-butylhydroperoxide as oxidizing agent. In the presence of avidin as host protein, the biotinylated aminosulfonamide ruthenium piano stool complex 1 (0.4 mol%) catalyzes the oxidation of...

Université de Neuchâtel

Artificial metalloenzymes : proteins as hosts for enantioselective catalysis

Ward, Thomas R. ; Thomas, Christophe M.

In: Chemical Society Reviews, 2005, vol. 34, p. 337-346

Enantioselective catalysis is one of the most efficient ways to synthesize high-added-value enantiomerically pure organic compounds. As the subtle details which govern enantioselection cannot be reliably predicted or computed, catalysis relies more and more on a combinatorial approach. Biocatalysis offers an attractive, and often complementary, alternative for the synthesis of enantiopure...