Université de Neuchâtel

Synthèse et application de sélecteurs chiraux à base de cyclodextrines en chromatographie gazeuse

Vaucher, Jean-Marc ; Tabacchi, Raffaele (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2006 ; 1918.

This study comprised the synthesis of cyclodextrin dimers substituted by entities such as acetyl, t-butyldimethylsilyl or alkyls in order to produce capillary columns for chiral analysis in gas chromatography. Production of dimeric compounds required the fabrication of monosubstituted monomers using selective pathways. Particular care was taken of the optimization of the various reactions. The...

Université de Neuchâtel

Synthèse de dérivés d’isocoumarines naturelles, métabolites du champignon pathogène Ceratocystis fimbriata sp.

Tiouabi, Mustapha ; Tabacchi, Raffaele (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2005 ; 1863.

During our research on phytotoxins produced by the Ceratocystis fimbriata species, pathogenic agent responsible for the infections of plane, coffee and elm tree, the analytical and spectroscopic studies allowed the isolation and identification of the isocoumarins a-f in small quantity. Our objective is the development of an efficient method for the total synthesis of a sufficient amount of these...

Université de Neuchâtel

Etude phytochimique et activités biologiques de quatre espèces camerounaises de la famille des Myrtaceae : Eucalyptus saligna Sm., Callistemon viminalis W., Syzygium guineense W. et Syzygium aromaticum M. et P.

Djoukeng, Jules Désiré ; Tabacchi, Raffaele (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2005 ; 1822.

Plants of the Myrtaceae family are aromatic and rich in essential oils, which explain their use in medicine. Some plants of this family are used traditonnally as post-harvest grain protectants in developing countries. In the aim to understand the traditional uses of Eucalyptus saligna Sm., Callistemon viminalis G., Syzygium guineense W. and Syzygium aromaticum Merr and Perry (Myrtaceae), we...

Université de Neuchâtel

Synthèse asymétrique de naphtalènones naturelles d'origine fongique

Couché, Emmanuel ; Tabacchi, Raffaele (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2001 ; 1592.

In our investigations on the phytotoxic substances involved in the diseases of plane tree, coffea, grapevine or ducth elm tree, several polyhydroxylated 3,4-dihydro naphthalen-1(2H)-ones that come from the biosynthesis of the fungal DHN-melanin have been isolated. Some of the substances, such as the 3,4-dihydro-2,4,8-trihydroxynaphthalen-1(2H)-one, developed deep necrosis on the plant cells. In...

Université de Neuchâtel

Isolation and identification of secondary metabolites from the fungus Phomopsis spp., a pathogen responsible for vine excoriosis = Isolement et identification de métabolites secondaires du champignon Phomosis spp., un pathogène responsable de l’excoriose de la vigne

Mottier, Nicolas ; Tabacchi, Raffaele (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2005 ; 1841.

Grapevine diseases are of great importance as they affect production and harvesting causing serious yield loss. The amount of damage or loss is often dependant on the climate of the region and the cultural practices of the grape growers. Control of these diseases is generally done using fungicide sprays and management techniques such as leaf plucking, pruning, etc. Epidemics do occur from time to...