Refine my results

Document type


Specific Collection



    Université de Fribourg

    Xenacoelomorpha survey reveals that all 11 animal homeobox gene classes were present in the first bilaterians

    Brauchle, Michael ; Bilican, Adem ; Eyer, Claudia ; Bailly, Xavier ; Martínez, Pedro ; Ladurner, Peter ; Bruggmann, Rémy ; Sprecher, Simon G.

    In: Genome Biology and Evolution, 2018, vol. 10, no. 9, p. 2205–2217

    Homeodomain transcription factors are involved in many developmental processes across animals and have been linked to body plan evolution. Detailed classifications of these proteins identified 11 distinct classes of homeodomain proteins in animal genomes, each harboring specific sequence composition and protein domains. Although humans contain the full set of classes, Drosophila melanogaster...

    Université de Fribourg

    Characterization of the bHLH family of transcriptional regulators in the acoel S. roscoffensis and their putative role in neurogenesis

    Perea?Atienza, E. ; Sprecher, Simon G. ; Martínez, Pedro

    In: EvoDevo, 2018, vol. 9, no. 1, p. -

    he basic helix-loop-helix (bHLH) family of transcription factors is one of the largest superfamilies of regulatory transcription factors and is widely used in eukaryotic organisms. They play an essential role in a range of metabolic, physiological, and developmental processes, including the development of the nervous system (NS). These transcription factors have been studied in many...