Université de Neuchâtel

Ecological immunity of "Anopheles gambiae" mosquitoes

Barreaux, Antoine ; Koella, Jacob (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2016.

Malaria is a vector borne disease caused by protozoan parasites and transmitted to humans by mosquitoes. It is one of the most deadly infectious diseases in the world, with more than one million deaths each year. Malaria is even more worrying in the context of climate change, as global warming is predicted to increase the transmission to humans and to influence vector-parasite interactions. To...

Université de Neuchâtel

The role of insecticides and malaria infection on the mosquito’s behaviour and the consequences for malaria transmission

Thiévent, Kevin ; Koella, Jacob (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2018.

Insecticide treated bed nets (ITNs) are one of the most cost-effective techniques used for malaria control. While the repellent and irritant actions of ITNs offer personal protection, their insecticidal action contributes to community protection by lowering the number of infectious mosquitoes in the population. Despite this, the efficacy of ITNs to provide both personal and community protection...

Université de Neuchâtel

Impact of environment on co-evolution between hosts and parasites

Zeller, Michael ; Koella, Jacob (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2016.

Many parasites cause pathology and mortality and can be a major source of selection on their hosts, creating strong selection pressures on the evolution of hosts defense strategies. Changes in the host’s tolerance and resistance to pathogen can strongly influence the spread of a disease and hence influence selection on virulence. Understanding how ecological conditions influence the host’s...