Université de Neuchâtel

Thioredoxin links redox to the regulation of fundamental processes of plant mitochondria

Balmer, Yves ; Vensel, William H. ; Tanaka, Charlene K. ; Hurkman, William J. ; Gelhaye, Eric ; Rouhier, Nicolas ; Jacquot, Jean-Pierre ; Manieri, Wanda ; Droux, Michel ; Schürmann, Peter ; Buchanan, Bob B.

In: Proceedings of the National Academy of Sciences of the United States of America (PNAS), 2004, vol. 101, no. 8, p. 2642-2647

Mitochondria contain thioredoxin (Trx), a regulatory disulfide protein, and an associated flavoenzyme, NADP/Trx reductase, which provide a link to NADPH in the organelle. Unlike animal and yeast counterparts, the function of Trx in plant mitochondria is largely unknown. Accordingly, we have applied recently devised proteomic approaches to identify soluble Trx-linked proteins in mitochondria...