Université de Fribourg

Are animals a source of Stenotrophomonas maltophilia in human infections? Contributions of a nationwide molecular study

Jayol, Aurélie ; Corlouer, Camille ; Haenni, Marisa ; Darty, Mélanie ; Maillard, Karine ; Desroches, Marine ; Lamy, Brigitte ; Jumas-Bilak, Estelle ; Madec, Jean-Yves ; Decousser, Jean-Winoc

In: European Journal of Clinical Microbiology & Infectious Diseases, 2018, p. 1–7

Stenotrophomonas maltophilia (Sm) is an archetypal environmental opportunistic bacterium responsible for health care-associated infections. The role of animals in human Sm infections is unknown. This study aims to reveal the genetic and phylogenetic relationships between pathogenic strains of Sm, both animal and human, and identify a putative role for animals as a reservoir in human...

Université de Fribourg

Acquisition of broad-spectrum cephalosporin resistance leading to colistin resistance in Klebsiella pneumoniae

Jayol, Aurélie ; Nordmann, Patrice ; Desroches, Marine ; Decousser, Jean-Winoc ; Poirel, Laurent

In: Antimicrobial Agents and Chemotherapy, 2016, vol. 60, no. 5, p. 3199–3201

An extended-spectrum β-lactamase (ESBL)-producing and colistin-resistant Klebsiella pneumoniae clinical isolate was recovered from a patient who was treated with cefotaxime. This isolate harbored a blaCTX-M-15 ESBL gene that was associated with an ISEcp1 insertion sequence. Transposition of that tandem occurred within the chromosomal mgrB gene, leading...