No exact match found for Mersch-Sundermann Volker, using Mersch Sundermann Volker instead...
Université de Fribourg

Cellular uptake and toxic effects of fine and ultrafine metal-sulfate particles in human A549 lung epithelial cells

Könczöl, Mathias ; Goldenberg, Ella ; Ebeling, Sandra ; Schäfer, Bianca ; Garcia-Käufer, Manuel ; Gminski, Richard ; Grobéty, Bernard ; Rothen-Rutishauser, Barbara ; Merfort, Irmgard ; Giere, Reto ; Mersch-Sundermann, Volker

In: Chemical Research in Toxicology, 2012, p. -

Ambient airborne particulate matter is known to cause various adverse health effects in humans. In a recent study on the environmental impacts of coal and tire combustion in a thermal power station fine crystals of PbSO4 (anglesite), ZnSO4•H2O (gunningite), and CaSO4 (anhydrite) were identified in the stack emissions. Here, we have studied the toxic potential of these sulfate phases as...

Université de Fribourg

cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in a549 human lung epithelial cells: role of ROS, JNK, and NF-κB

Könczöl, Mathias ; Ebeling, Sandra ; Goldenberg, Ella ; Treude, Fabian ; Gminski, Richard ; Gieré, Reto ; Bernard Grobéty ; Rothen-Rutishauser,, Barbara ; Merfort, Irmgard ; Mersch-Sundermann, Volker

In: Chemical Research in Toxycology, 2011, vol. 24, no. 9, p. 1460–1475

Airborne particulate matter (PM) of varying size and composition is known to cause health problems in humans. The iron oxide Fe₃O₄ (magnetite) may be a major anthropogenic component in ambient PM and is derived mainly from industrial sources. In the present study, we have investigated the effects of four different size fractions of magnetite on signaling pathways, free radical generation,...

Université de Fribourg

Genotoxic effects of three selected black toner powders and their dimethyl sulfoxide extracts in cultured human epithelial A549 lung cells in vitro

Gminski, Richard ; Decker, Katharina ; Heinz, Christina ; Seidel, Albrecht ; Könczöl, Mathias ; Goldenberg, Ella ; Grobéty, Bernard ; Ebner, Winfried ; Gieré, Reto ; Mersch-Sundermann, Volker

In: Environmental and Molecular Mutagenesis, 2011, vol. 52, p. 296–309

Until now, the adverse effects of toner powders on humans have been considered to be minimal. However, several recent reports have suggested possible significant adverse health effects from toner dust inhalation. The aim of this study was to evaluate the genotoxic potential of black toner powders in vitro. For the study of DNA damage, A549 cells were exposed to toner-powder suspensions and to...