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Sugar-sensitive neurone responses and sugar feeding preferences influence lifespan and biting behaviours of the Afrotropical malaria mosquito, Anopheles gambiae

Kessler, Sébastien ; Vlimant, Michèle ; Guerin, Patrick

In: Journal of Comparative Physiology A, 2015, vol. 201, no. 3, p. 317-329

Two sides of the same coin: A population genetics perspective on lethal mutagenesis and mutational meltdown

Matuszewski, Sebastian ; Ormond, Louise ; Bank, Claudia ; Jensen, Jeffrey D.

In: Virus Evolution, 2017, vol. 3, no. 1, p. -

From Agricultural Benefits to Aviation Safety: Realizing the Potential of Continent-Wide Radar Networks

Bauer, Silke ; Chapman, Jason W. ; Reynolds, Don R. ; Alves, José A. ; Dokter, Adriaan M. ; Menz, Myles M. H. ; Sapir, Nir ; Ciach, Michał ; Pettersson, Lars B. ; Kelly, Jeffrey F. ; Leijnse, Hidde ; Shamoun-Baranes, Judy

In: BioScience, 2017, vol. 67, no. 10, p. 912-918

Sterile-filtered saliva is a strong inducer of IL-6 and IL-8 in oral fibroblasts

Cvikl, Barbara ; Lussi, Adrian ; Moritz, Andreas ; Sculean, Anton ; Gruber, Reinhard

In: Clinical Oral Investigations, 2015, vol. 19, no. 2, p. 385-399

A distributionally robust perspective on uncertainty quantification and chance constrained programming

Hanasusanto, Grani ; Roitch, Vladimir ; Kuhn, Daniel ; Wiesemann, Wolfram

In: Mathematical Programming, 2015, vol. 151, no. 1, p. 35-62

Cortical region-specific sleep homeostasis in mice: effects of time of day and waking experience

Guillaumin, Mathilde C C. ; McKillop, Laura E. ; Cui, Nanyi ; Fisher, Simon P. ; Foster, Russell G. ; de Vos, Maarten ; Peirson, Stuart N. ; Achermann, Peter ; Vyazovskiy, Vladyslav V.

In: SLEEP, 2018, vol. 41, no. 7, p. -

Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions

Marques, Filipe ; Thapliyal, Saurabh ; Javer, Avelino ; Shrestha, Priyanka ; Brown, André E. X. ; Glauser, Dominique A.

In: PLOS Genetics, 2020, vol. 16, no. 10, p. e1009102

Ryanodine receptors (RyR) are essential regulators of cellular calcium homeostasis and signaling. Vertebrate genomes contain multiple RyR gene isoforms, expressed in different tissues and executing different functions. In contrast, invertebrate genomes contain a single RyR-encoding gene and it has long been proposed that different transcripts generated by alternative splicing may diversify...

Inference of natural selection from ancient DNA

Dehasque, Marianne ; Ávila‐Arcos, María C. ; Díez‐del‐Molino, David ; Fumagalli, Matteo ; Guschanski, Katerina ; Lorenzen, Eline D. ; Malaspinas, Anna‐Sapfo ; Marques‐Bonet, Tomas ; Martin, Michael D. ; Murray, Gemma G. R. ; Papadopulos, Alexander S. T. ; Therkildsen, Nina Overgaard ; Wegmann, Daniel ; Dalén, Love ; Foote, Andrew D.

In: Evolution Letters, 2020, vol. 4, no. 2, p. 94–108

Evolutionary processes, including selection, can be indirectly inferred based on patterns of genomic variation among contemporary populations or species. However, this often requires unrealistic assumptions of ancestral demography and selective regimes. Sequencing ancient DNA from temporally spaced samples can inform about past selection processes, as time series data allow direct...

In vivo function of the lipid raft protein flotillin-1 during cd8+ t cell–mediated host surveillance

Ficht, Xenia ; Ruef, Nora ; Stolp, Bettina ; Samson, Guerric P. B. ; Moalli, Federica ; Page, Nicolas ; Merkler, Doron ; Nichols, Ben J. ; Diz-Muñoz, Alba ; Legler,, Daniel F. ; Niggli, Verena

In: The Journal of Immunology, 2019, p. -

Flotillin-1 (Flot1) is an evolutionary conserved, ubiquitously expressed lipid raft– associated scaffolding protein. Migration of Flot1-deficient neutrophils is impaired because of a decrease in myosin II–mediated contractility. Flot1 also accumulates in the uropod of polarized T cells, suggesting an analogous role in T cell migration. In this study, we analyzed morphology and migration...

Predicting abundances of invasive ragweed across Europe using a “top-down” approach

Skjøth, Carsten Ambelas ; Sun, Yan ; Karrer, Gerhard ; Sikoparija, Branko ; Smith, Matt ; Schaffner, Urs ; Müller-Schärer, Heinz

In: Science of The Total Environment, 2019, vol. 686, p. 212–222

Common ragweed (Ambrosia artemisiifolia L.) is a widely distributed and harmful invasive plant that is an important source of highly allergenic pollen grains and a prominent crop weed. As a result, ragweed causes huge costs to both human health and agriculture in affected areas. Efficient mitigation requires accurate mapping of ragweed densities that, until now, has not been achieved...