Public access from 20.02.2020
Università della Svizzera italiana

DNA (hydroxy)methylation in T helper lymphocytes

Monticelli, Silvia

In: Trends in biochemical sciences, 2019, vol. 44, no. 7, p. 589-598

Upon recognition of an antigen, the differentiation of antigen-inexperienced naïve T lymphocytes into subsets able to effectively coordinate host defense is controlled by a network of transcription factors and regulatory molecules. In the cell nucleus, these factors act in the context of epigenetic modifications that influence DNA accessibility and ultimately gene expression. This review...

Università della Svizzera italiana

Epigenetics of T lymphocytes in health and disease

Leoni, Cristina ; Vincenzetti, Lucia ; Emming, Stefan ; Monticelli, Silvia

In: Swiss Medical weekly, 2015, vol. 145, p. w14191

The risk of developing autoimmune diseases depends on both genetic and environmental factors, with epigenetic mechanisms of regulation potentially translating environmental cues into stable modifications in gene expression. Such stable memory of a functional state has been deciphered into a number of molecular mechanisms that collectively define the epigenetic status of a cell. In recent years,...

Consortium of Swiss Academic Libraries

Glioblastoma stem cells

Tabatabai, Ghazaleh ; Weller, Michael

In: Cell and Tissue Research, 2011, vol. 343, no. 3, p. 459-465

Consortium of Swiss Academic Libraries

Molecular markers in gliomas: impact for the clinician

Hofer, Silvia ; Lassman, Andrew

In: Targeted Oncology, 2010, vol. 5, no. 3, p. 201-210