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Université de Fribourg

Behavioral Responses to Uncertainty in Weight-Restored Anorexia Nervosa – Preliminary Results

Piccolo, Mayron ; Milos, Gabriella Franca ; Bluemel, Sena ; Schumacher, Sonja ; Mueller-Pfeiffer, Christoph ; Fried, Michael ; Ernst, Monique ; Martin-Soelch, Chantal

In: Frontiers in Psychology, 2019, p. 1-5

Impaired decision-making under conditions of uncertainty seems to contribute to theexpression and maintenance of anorexia nervosa (AN), but it is not clear whether thisimpairment is a disease state that would remit with treatment, or a persisting trait inpatients with AN. To examine this question, a longitudinal study was conducted in12 female inpatients with AN (age M = 22.2, SE = 1.36), before...

Université de Fribourg

Biological sex influences antibody responses to routine vaccinations in the first year of life

Zimmermann, Petra ; Perrett, Kirsten P. ; Ritz,  Nicole ; Flanagan, Katie L. ; Robins-Browne, Roy ; Klis, Fiona R. M. van der ; Curtis, Nigel ; the MIS BAIR group

In: Acta Paediatrica, 2019, p. -

Aim We investigated the effect of early-life factors, namely sex, delivery mode, feeding method and antibiotic exposure, on antibody responses to routine vaccinations administered during the first year of life. Methods One and seven months after the primary course of routine vaccines and 1 month after routine vaccines at 12 months of age, antibodies against 26 vaccine antigens were measured...

Université de Fribourg

Large-scale analysis of the mycoplasma bovis genome identified non-essential, adhesion- and virulence-related genes

Josi, Christoph ; Bürki, Sibylle ; Vidal, Sara ; Dordet-Frisoni, Emilie ; Citti, Christine ; Falquet, Laurent ; Pilo, Paola

In: Frontiers in Microbiology, 2019, vol. 10, p. -

Mycoplasma bovis is an important pathogen of cattle causing bovine mycoplasmosis. Clinical manifestations are numerous, but pneumonia, mastitis, and arthritis cases are mainly reported. Currently, no efficient vaccine is available and antibiotic treatments are not always satisfactory. The design of new, efficient prophylactic and therapeutic approaches requires a better understanding of the...

Haute école de santé Genève

Lombalgie chronique non spécifique : le yoga est-il plus efficace que la thérapie conventionnelle par l'exercice ? Effets comparés sur la douleur, l'incapacité fonctionnelle et la qualité de vie : une revue de la littérature : travail de Bachelor

Brunier, Pascal ; Graffin, Jérôme ; Leuridan, Yvan (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2019.

Introduction : la lombalgie chronique non spécifique constitue actuellement l’affection musculo-squelettique la plus répandue dans le monde. Les recommandations actuelles pour la prise en charge physiothérapeutique soulignent l’importance d’une rééducation active dans le traitement de cette affection chronique. Dans une perspective d’amélioration des soins de physiothérapie,...

Haute école de santé Genève

Programme de course à pied avec feedback visuel : que est l'intérêt sur le taux de mise en charge au sol chez les coureurs adultes : travail de Bachelor

Streit, Romain ; Maire, Sophie ; Gard, Suzanne (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2019.

Introduction : La course à pied est pratiquée à travers le monde mais fait partie des dix sports avec la plus haute incidence de blessures. Le taux de mise en charge du pied au sol a été corrélé à une augmentation du risque de développer une fracture de stress tibiale ou à une récidive. Ainsi, une approche consistant en un programme de course à pied avec feedback visuel pourrait être...

Università della Svizzera italiana

Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus

Sastry, Mallika ; Zhang, Baoshan ; Chen, Man ; Joyce, M. Gordon ; Kong, Wing-Pui ; Chuang, Gwo-Yu ; Ko, Kiyoon ; Kumar, Azad ; Silacci, Chiara ; Thom, Michelle ; Salazar, Andres M. ; Corti, Davide ; Lanzavecchia, Antonio ; Taylor, Geraldine ; Mascola, John R. ; Graham, Barney S. ; Kwong, Peter D.

In: Plos one, 2017, vol. 12, no. 10, p. e0186854

Appropriate adjuvant selection may be essential to optimize the potency and to tailor the immune response of subunit vaccines. To induce protective responses against respiratory syncytial virus (RSV)—a highly prevalent childhood pathogen without a licensed vaccine—we previously engineered a pre-fusion-stabilized trimeric RSV F (pre-F) “DS-Cav1” immunogen, which induced high titer...

Università della Svizzera italiana

Epicutaneous allergen application preferentially boosts specific T cell responses in sensitized patients

Campana, Raffaela ; Moritz, Katharina ; Neubauer, Angela ; Huber, Hans ; Henning, Rainer ; Brodie, Tess M. ; Kaider, Alexandra ; Sallusto, Federica ; Wöhrl, Stefan ; Valenta, Rudolf

In: Scientific reports, 2017, vol. 7, p. 11657

The effects of epicutaneous allergen administration on systemic immune responses in allergic and non-allergic individuals has not been investigated with defined allergen molecules. We studied the effects of epicutaneous administration of rBet v 1 and rBet v 1 fragments on systemic immune responses in allergic and non-allergic subjects. We conducted a clinical trial in which rBet v 1 and two...

Université de Fribourg

The effects of gender and parental occupation in the apprenticeship market : an experimental evaluation

Fernandes, Ana ; Huber, Martin ; Plaza, Camila

(Working Papers SES ; 506)

The apprenticeship market is the earliest possible entry into the workforce in developed economies. Since early labor market shocks are likely magnified throughout professional life, avoiding mismatches between talent and occupations e.g. due to gender- or status-based discrimination appears crucial. This experimental study investigates the effects of applicant gender and its interaction with...

Università della Svizzera italiana

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Zhang, Baoshan ; Chen, Lei ; Silacci, Chiara ; Thom, Michelle ; Boyington, Jeffrey C. ; Druz, Aliaksandr ; Joyce, M. Gordon ; Guzman, Efrain ; Kong, Wing-Pui ; Lai, Yen-Ting ; Stewart-Jones, Guillaume B. E. ; Tsybovsky, Yaroslav ; Yang, Yongping ; Zhou, Tongqing ; Baxa, Ulrich ; Mascola, John R. ; Corti, Davide ; Lanzavecchia, Antonio ; Taylor, Geraldine ; Kwong, Peter D.

In: Npj vaccines, 2017, vol. 2, p. 7

Bovine respiratory syncytial virus, a major cause of respiratory disease in calves, is closely related to human RSV, a leading cause of respiratory disease in infants. Recently, promising human RSV-vaccine candidates have been engineered that stabilize the metastable fusion (F) glycoprotein in its prefusion state; however, the absence of a relevant animal model for human RSV has complicated...

Université de Fribourg

Absorb bioresorbable scaffold versus xience metallic stent for prevention of restenosis following percutaneous coronary intervention in patients at high risk of restenosis: rationale and design of the COMPARE ABSORB trial

Chang, Chun Chin ; Onuma, Yoshinobu ; Achenbach, Stephan ; Barbato, Emanuele ; Chevalier, Bernard ; Cook, Stéphane ; Dudek, Dariusz ; Escaned, Javier ; Gori, Tommaso ; Kočka, Viktor ; Tarantini, Giuseppe ; E.J.West, Nick ; Morice, Marie-Claude ; G.P.Tijssen, Jan ; Geuns, Robert-Janvan ; C.Smits, Pieter

In: Cardiovascular Revascularization Medicine, 2019, vol. 20, no. 7, p. 577–582

Background: The advent of bioresorbable vascular scaffolds (BVS) was considered as a potential improvement in percutaneous coronary intervention (PCI) after the groundbreaking development of drug eluting stents (DES). However, the clinical performance, long-term safety and efficacy of BVS in complex coronary lesions remain uncertain. COMPARE ABSORB, a multicenter, single blind, prospective ...