In: Journal of Infectious Diseases, ///-
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In: The American Journal of Clinical Nutrition, 2016, vol. 103, no. 2, p. 348-355
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In: Physica A: Statistical Mechanics and its Applications, 2019, vol. 536, p. 121004
When the product quality is limited and the information capability is variable, we propose the enterprise enhances corporate profits by changing the relationship between market demand and external resources. We assume that the information capacity can be changed through the input of external resources. In this paper, we present a research agenda that empowers external resources to transform...
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In: Physical Review A, 2019, vol. 99, no. 4, p. 042112
Magnetic-field uniformity is of the utmost importance in experiments to measure the electric dipole moment of the neutron. A general parametrization of the magnetic field in terms of harmonic polynomial modes is proposed, going beyond the linear- gradients approximation. We review the main undesirable effects of nonuniformities: depolarization of ultracold neutrons and Larmor frequency shifts...
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In: Plos pathogens, 2011, vol. 7, no. 9, p. e1002231
Alteration of early haematopoietic development is thought to be responsible for the onset of immature leukemias and lymphomas. We have previously demonstrated that TaxHTLV-1 interferes with ß- selection, an important checkpoint of early thymopoiesis, indicating that human T-cell leukemia virus type 1 (HTLV-1) infection has the potential to perturb thymic human αβ T-cell development. To...
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In: Plos one, 2011, vol. 6, no. 3, p. e18207
Neutralizing antibodies have been shown to protect macaques against SHIV challenge. However, genetically diverse HIV-1 clades have evolved, and a key question left unanswered is whether neutralizing antibodies can confer cross-clade protection in vivo. The novel human monoclonal antibody HGN194 was isolated from an individual infected with an HIV-1 clade AG recombinant circulating recombinant...
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In: Plos pathogens, 2010, vol. 6, no. 11, p. e1001195
The human monoclonal antibody (mAb) HK20 neutralizes a broad spectrum of primary HIV-1 isolates by targeting the highly conserved heptad repeat 1 (HR1) of gp41, which is transiently exposed during HIV-1 entry. Here we present the crystal structure of the HK20 Fab in complex with a gp41 mimetic 5-Helix at 2.3 A° resolution. HK20 employs its heavy chain CDR H2 and H3 loops to bind into a...
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In: Plos one, 2010, vol. 5, no. 1, p. e8805
Background The isolation of human monoclonal antibodies (mAbs) that neutralize a broad spectrum of primary HIV-1 isolates and the characterization of the human neutralizing antibody B cell response to HIV-1 infection are important goals that are central to the design of an effective antibody-based vaccine. Methods and Findings We immortalized IgG+ memory B cells from individuals infected with...
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In: Lecture Notes in Computer Science, 2016, vol. 9849, p. 38-49
We consider the following problem: can a certain graph parameter of some given graph G be reduced by at least d, for some integer d, via at most k graph operations from some specified set S, for some given integer k? As graph parameters we take the chromatic number and the clique number. We let the set S consist of either an edge contraction or a vertex deletion. As all these problems are...
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In: Surveys in Geophysics, 2011, vol. 32, no. 4-5, p. 437-458
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