Ergebnisse einschränken

Targeting glycolysis in macrophages confers protection against pancreatic ductal adenocarcinoma

Penny, Hweixian Leong ; Sieow, Je Lin ; Gun, Sin Yee ; Lau, Mai Chan ; Lee, Bernett ; Tan, Jasmine ; Phua, Cindy ; Toh, Florida ; Nga, Yvonne ; Yeap, Wei Hseun ; Janela, Baptiste ; Kumar, Dilip ; Chen, Hao ; Yeong, Joe ; Kenkel, Justin A. ; Pang, Angela ; Lim, Diana ; Toh, Han Chong ; Hon, Tony Lim Kiat ; Johnson, Christopher I. ; Khameneh, Hanif Javanmard ; Mortellaro, Alessandra ; Engleman, Edgar G. ; Rotzschke, Olaf ; Ginhoux, Florent ; Abastado, Jean-Pierre ; Chen, Jinmiao ; Wong, Siew Cheng

In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24

Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...

6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice

Jeanbart, Laura ; Kourtis, Iraklis ; van der Vlies, André ; Swartz, Melody ; Hubbell, Jeffrey

In: Cancer Immunology, Immunotherapy, 2015, vol. 64, no. 8, p. 1033-1046

Insulin-like growth factor I is expressed in classical and nodular lymphocyte-predominant Hodgkin's lymphoma tumour and microenvironmental cells

Eppler, Elisabeth ; Janas, Eva ; Link, Karl ; Weidmann, Lukas ; Bischofberger, Helena ; Wenger, Michael ; Tinguely, Marianne ; Schraml, Peter ; Moch, Holger ; Fellbaum, Christian

In: Cell and Tissue Research, 2015, vol. 359, no. 3, p. 841-851

N -methyl pyrrolidone (NMP) inhibits lipopolysaccharide-induced inflammation by suppressing NF-κB signaling

Ghayor, Chafik ; Gjoksi, Bebeka ; Siegenthaler, Barbara ; Weber, Franz

In: Inflammation Research, 2015, vol. 64, no. 7, p. 527-536

Efficacy, effectiveness and safety of long-acting granulocyte colony-stimulating factors for prophylaxis of chemotherapy-induced neutropenia in patients with cancer: a systematic review

Pfeil, Alena ; Allcott, Kim ; Pettengell, Ruth ; von Minckwitz, Gunter ; Schwenkglenks, Matthias ; Szabo, Zsolt

In: Supportive Care in Cancer, 2015, vol. 23, no. 2, p. 525-545

Individual learning performance and exploratory activity are linked to colony foraging success in a mass-recruiting ant

Pasquier, Grégoire ; Grüter, Christoph

In: Behavioral Ecology, 2016, vol. 27, no. 6, p. -

Postmortem serum protein growth arrest-specific 6 levels in sepsis-related deaths

Palmiere, Cristian ; Augsburger, Marc

In: International Journal of Legal Medicine, 2015, vol. 129, no. 5, p. 1079-1084

Formation and role of exosomes in cancer

Brinton, Lindsey ; Sloane, Hillary ; Kester, Mark ; Kelly, Kimberly

In: Cellular and Molecular Life Sciences, 2015, vol. 72, no. 4, p. 659-671

Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60

Tonello, Lucio ; Conway de Macario, Everly ; Marino Gammazza, Antonella ; Cocchi, Massimo ; Gabrielli, Fabio ; Zummo, Giovanni ; Cappello, Francesco ; Macario, Alberto

In: Cell Stress and Chaperones, 2015, vol. 20, no. 2, p. 391-395

FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase

Imeri, Faik ; Blanchard, Olivier ; Jenni, Aurelio ; Schwalm, Stephanie ; Wünsche, Christin ; Zivkovic, Aleksandra ; Stark, Holger ; Pfeilschifter, Josef ; Huwiler, Andrea

In: Naunyn-Schmiedeberg's Archives of Pharmacology, 2015, vol. 388, no. 12, p. 1283-1292